Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | APAF1 | O14727 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | FPR2 | P25090 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL14744145 | 0.92 | RAB9A (0.49) | RAB9ASMN1; SMN2LMNAKMT2ANPC1 | |
| SCHEMBL13580921 | 0.88 | RAB9A (0.56) | RAB9ASMN1; SMN2LMNAKMT2ANPC1 | |
| SCHEMBL2587839 | 0.85 | RAB9A (0.44) | RAB9ASMN1; SMN2LMNAKMT2ANPC1 | |
| Cyanide SCHEMBL28172176 | 0.80 | EPHX1 (0.46) | RAB9ASMN1; SMN2LMNAKMT2ANPC1 | |
| SCHEMBL11526739 | 0.78 | MAPT (0.63) | RAB9ASMN1; SMN2LMNAKMT2ANPC1 | |
| SCHEMBL25041451 | 0.76 | KDM1A (0.51) | RAB9ASMN1; SMN2LMNAKMT2ANPC1 | |
| SCHEMBL18129725 | 0.76 | KDM1A (0.51) | RAB9ASMN1; SMN2LMNAKMT2ANPC1 | |
| SCHEMBL18318908 | 0.76 | FPR2 (0.47) | RAB9ASMN1; SMN2LMNAHDAC8FPR2 | |
| SCHEMBL3400048 | 0.75 | MAPT (0.61) | RAB9ASMN1; SMN2LMNAKMT2ANPC1 | |
| SCHEMBL78145 | 0.75 | MAPT (0.61) | RAB9ASMN1; SMN2LMNAKMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108473471-A | Substituted thiourocystine derivatives as androgen receptor antagonists | 詹森药业有限公司 | 2018-08-31 | — | — | CN | disclosed |