Chalcone

Chalcone

SCHEMBL28237996

NC(Cc1ccccc1)C(=O)O.O=C(C=Cc1ccccc1)c1ccccc1

nearest known ligand 0.63

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1B1 Q16678 6/20 0.63
MAPT P10636 4/20 0.63
MAOB P27338 4/20 0.63
PKM P14618 2/20 0.63
PLIN1 O60240 1/20 0.63
LMNA P02545 1/20 0.63
BCHE P06276 1/20 0.63
TNFRSF1A P19438 1/20 0.63
ACHE P22303 1/20 0.63
RECQL P46063 1/20 0.63
PLIN5 Q00G26 1/20 0.63
ABHD5 Q8WTS1 1/20 0.63
ALPI P09923 1/20 0.63
PTGS1 P23219 1/20 0.63
XIAP P98170 1/20 0.63
SLC7A5 Q01650 1/20 0.63
CYP3A4 P08684 3/20 0.53
KMT2A Q03164 3/20 0.53
HSPD1 P10809 2/20 0.53
HSPE1 P61604 2/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dl-Phenylalanine SCHEMBL8012735 0.87 SLC7A5 (0.69) PKMLMNAALPIPTGS1XIAP
Phenylalanine SCHEMBL8012741 0.87 SLC7A5 (0.69) PKMLMNAALPIPTGS1XIAP
Phenylalanine SCHEMBL8012746 0.87 SLC7A5 (0.69) PKMLMNAALPIPTGS1XIAP
Phenylalanine SCHEMBL17023916 0.85 SLC7A5 (0.67) PKMLMNAALPIPTGS1XIAP
SCHEMBL5332108 0.82 SLC7A5 (0.70) MAPTPKMLMNAACHERECQL
SCHEMBL31025610 0.82 SLC7A5 (0.70) MAPTPKMLMNAACHERECQL
Juarezic Acid SCHEMBL29070019 0.80 SLC7A5 (0.63) MAPTMAOBPKMALPIPTGS1
SCHEMBL23159186 0.79 SLC7A5 (1.00) PKMRECQLALPIPTGS1XIAP
Dl-Phenylalanine SCHEMBL385804 0.79 SLC7A5 (1.00) PKMRECQLALPIPTGS1XIAP
Dl-Phenylalanine SCHEMBL16398196 0.79 SLC7A5 (1.00) PKMRECQLALPIPTGS1XIAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108503699-A Chinese wolfberry gene and its coding protein, recombinant vector and use 中国科学院西北高原生物研究所 2018-09-07 CN disclosed