Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | DNTT | P04053 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TLR4 | O00206 | 1/20 | 0.40 |
| ▸ | NAAA | Q02083 | 3/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | POLA1 | P09884 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hexane SCHEMBL28557946 | 0.95 | TSHR (0.43) | MAPK1DNTTTSHRHTTSMN1; SMN2 | |
| SCHEMBL20303983 | 0.90 | MAPK1 (0.54) | MAPK1HTTSMN1; SMN2MCL1KDM4E | |
| SCHEMBL7305358 | 0.90 | MAPK1 (0.54) | MAPK1HTTSMN1; SMN2MCL1KDM4E | |
| SCHEMBL3171 | 0.90 | MAPK1 (0.54) | MAPK1HTTSMN1; SMN2MCL1KDM4E | |
| SCHEMBL28194940 | 0.89 | MAPK1 (0.41) | MAPK1DNTTTSHRHTTSMN1; SMN2 | |
| SCHEMBL6248372 | 0.88 | MAPK1 (0.53) | MAPK1HTTSMN1; SMN2MCL1KDM4E | |
| SCHEMBL1615850 | 0.88 | MAPK1 (0.53) | MAPK1HTTSMN1; SMN2MCL1KDM4E | |
| SCHEMBL3767660 | 0.88 | MAPK1 (0.53) | MAPK1HTTSMN1; SMN2MCL1KDM4E | |
| SCHEMBL27922653 | 0.88 | MAPK1 (0.53) | MAPK1HTTSMN1; SMN2MCL1KDM4E | |
| SCHEMBL7199566 | 0.88 | MAPK1 (0.53) | MAPK1HTTSMN1; SMN2MCL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106008322-B | sulfonamide derivatives as BC L-2-selective apoptosis-inducing agents for the treatment of cancer and immune diseases | ABBVIE 公司 | 2018-09-04 | — | — | CN | disclosed |