Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA4 | P22748 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6248372 | 1.00 | MAPK1 (0.53) | MAPK1KDM4EHSD17B10MCL1KMT2A | |
| SCHEMBL1615850 | 1.00 | MAPK1 (0.53) | MAPK1KDM4EHSD17B10MCL1KMT2A | |
| SCHEMBL27922653 | 1.00 | MAPK1 (0.53) | MAPK1KDM4EHSD17B10MCL1KMT2A | |
| SCHEMBL3767660 | 1.00 | MAPK1 (0.53) | MAPK1KDM4EHSD17B10MCL1KMT2A | |
| SCHEMBL3171 | 0.98 | MAPK1 (0.54) | MAPK1KDM4EHSD17B10MCL1KMT2A | |
| SCHEMBL20303983 | 0.98 | MAPK1 (0.54) | MAPK1KDM4EHSD17B10MCL1KMT2A | |
| SCHEMBL7305358 | 0.98 | MAPK1 (0.54) | MAPK1KDM4EHSD17B10MCL1KMT2A | |
| SCHEMBL25061 | 0.92 | MAPK1 (0.47) | MAPK1KDM4EHSD17B10MCL1CA1 | |
| SCHEMBL31276435 | 0.92 | MAPK1 (0.47) | MAPK1KDM4EHSD17B10MCL1CA1 | |
| SCHEMBL374935 | 0.92 | MAPK1 (0.47) | MAPK1KDM4EHSD17B10MCL1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030078455-A1 | Processes for the preparation of macrocyclic ketones | JAPAN ENERGY CORPORATION (JP) | 2003-04-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030078455-A1 | Processes for the preparation of macrocyclic ketones | TKT, DTYMK, BCKDK | MAPK1 3477/4885KDM4E 543/4885HSD17B10 491/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.