SCHEMBL1615850

SCHEMBL1615850

COC(=O)C1CCCCCC1=O

nearest known ligand 0.53

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.53
KDM4E B2RXH2 1/20 0.49
HSD17B10 Q99714 1/20 0.49
MCL1 Q07820 1/20 0.47
KMT2A Q03164 1/20 0.45
CA1 P00915 2/20 0.42
CA2 P00918 2/20 0.42
CA4 P22748 2/20 0.42
HTT P42858 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.39
POLB P06746 2/20 0.37
USP2 O75604 1/20 0.37
ALDH1A1 P00352 1/20 0.37
LMNA P02545 1/20 0.37
CA6 P23280 1/20 0.36
SLC6A2 P23975 2/20 0.36
SLC6A4 P31645 1/20 0.36
CYP2D6 P10635 1/20 0.36
CYP1A2 P05177 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7199566 1.00 MAPK1 (0.53) MAPK1KDM4EHSD17B10MCL1KMT2A
SCHEMBL6248372 1.00 MAPK1 (0.53) MAPK1KDM4EHSD17B10MCL1KMT2A
SCHEMBL27922653 1.00 MAPK1 (0.53) MAPK1KDM4EHSD17B10MCL1KMT2A
SCHEMBL3767660 1.00 MAPK1 (0.53) MAPK1KDM4EHSD17B10MCL1KMT2A
SCHEMBL3171 0.98 MAPK1 (0.54) MAPK1KDM4EHSD17B10MCL1KMT2A
SCHEMBL20303983 0.98 MAPK1 (0.54) MAPK1KDM4EHSD17B10MCL1KMT2A
SCHEMBL7305358 0.98 MAPK1 (0.54) MAPK1KDM4EHSD17B10MCL1KMT2A
SCHEMBL25061 0.92 MAPK1 (0.47) MAPK1KDM4EHSD17B10MCL1CA1
SCHEMBL31276435 0.92 MAPK1 (0.47) MAPK1KDM4EHSD17B10MCL1CA1
SCHEMBL374935 0.92 MAPK1 (0.47) MAPK1KDM4EHSD17B10MCL1CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 246 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240400792-A1 CURABLE (METH)ACRYLATE COMPOSITIONS HENKEL AG & CO KGAA (DE) 2024-12-05 US claimed
CN-118355086-A Curable (meth) acrylate composition 汉高股份有限及两合公司 2024-07-16 CN claimed
WO-2023104819-A1 CURABLE (METH) ACRYLATE COMPOSITIONS Henkel IP & Holding GmbH (DE) 2023-06-15 WO claimed
US-20240400792-A1 CURABLE (METH)ACRYLATE COMPOSITIONS HENKEL AG & CO KGAA (DE) 2024-12-05 US disclosed
US-20240294542-A1 NLRP3 INFLAMMASOME INHIBITOR AND APPLICATION THEREOF TRANSTHERA SCIENCES (NANJING), INC. (CN) 2024-09-05 US disclosed
CN-118355086-A Curable (meth) acrylate composition 汉高股份有限及两合公司 2024-07-16 CN disclosed
CN-115667244-B 3-azabicycloalkyl derivatives and pharmaceutical compositions containing the same 株式会社LG化学 2024-04-12 CN disclosed
US-20230203008-A1 3-AZABICYCLOALKYL DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME LG CHEM, LTD. (KR) 2023-06-29 US disclosed
WO-2023104819-A1 CURABLE (METH) ACRYLATE COMPOSITIONS Henkel IP & Holding GmbH (DE) 2023-06-15 WO disclosed
EP-4134366-A1 3-AZABICYCLOALKYL DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME Lg Chem, Ltd. (KR) 2023-02-15 EP disclosed
CN-115667244-A 3-azabicycloalkyl derivatives and pharmaceutical compositions comprising the same 株式会社LG化学 2023-01-31 CN disclosed
US-5262385-A Pyrimidine ring containing MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1993-11-16 US disclosed
US-5234936-A Treating hypertension, congestive heart failure, hyperlipidemia and hypercholesterolemia AMERICAN HOME PRODUCTS CORPORATION (US) 1993-08-10 US disclosed
EP-0324646-B1 AZOLE-SUBSTITUTED CYCLOALKANOL DERIVATIVES, A PROCESS FOR PRODUCING THE SAME AND A USE OF THE DERIVATIVES AS AN AGRICULTURAL AND HORTICULTURAL FUNGICIDE KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1993-05-19 EP disclosed
WO-1993008171-A1 PYRIMIDOCYCLOALKANES AS ANGIOTENSIN II ANTAGONISTS AMERICAN HOME PRODUCTS CORPORATION (US) 1993-04-29 WO disclosed
US-5095028-A Fungicides KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1992-03-10 US disclosed
EP-0468766-A1 Halogen-containing compounds, herbicidal composition containing the same as an active ingredient, and intermediary compounds therefor Mitsubishi Chemical Corporation (JP) 1992-01-29 EP disclosed
US-4973354-A AGRICULTURE, OPTICAL ISOMERS NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 1990-11-27 US disclosed
US-4920138-A AGRICULTURAL AND HORTICULTURAL FUNGICIDES KUREHA KAGAKU KOGYO KABUSHIKI KAISHI (JP) 1990-04-24 US disclosed
EP-0324646-A2 Azole-substituted cycloalkanol derivatives, a process for producing the same and a use of the derivatives as an agricultural and horticultural fungicide KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1989-07-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240294542-A1 NLRP3 INFLAMMASOME INHIBITOR AND APPLICATION THEREOF NLRP3, NLRP1, PYCARD MAPK1 300/4885KDM4E 3867/4885HSD17B10 1551/4885
US-20230203008-A1 3-AZABICYCLOALKYL DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, ADCY1, ADCY7 MAPK1 786/4885KDM4E 2027/4885HSD17B10 332/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.