Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX4 | Q99571 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31003502 | 0.84 | MEN1 (0.35) | TDP1 | |
| SCHEMBL5792018 | 0.79 | LMNA (0.32) | — | |
| SCHEMBL16685632 | 0.73 | HTT (0.43) | P2RX4 | |
| SCHEMBL7041384 | 0.72 | P2RX4 (0.35) | P2RX4 | |
| SCHEMBL11129882 | 0.70 | P2RX4 (0.40) | P2RX4CYP1A2TDP1 | |
| SCHEMBL886893 | 0.69 | SIGMAR1 (0.36) | P2RX4TDP1 | |
| SCHEMBL30843927 | 0.69 | SIGMAR1 (0.36) | P2RX4TDP1 | |
| SCHEMBL2263869 | 0.68 | KDM4E (0.32) | P2RX4 | |
| SCHEMBL31006068 | 0.68 | KDM4E (0.32) | P2RX4 | |
| SCHEMBL3541130 | 0.68 | LMNA (0.34) | P2RX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108484632-A | Artemisinin-anilinoquinazoline derivatives, and preparation method and application thereof | 中国科学院昆明植物研究所 | 2018-09-04 | — | — | CN | claimed |