Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | CTSA | P10619 | 6/20 | 0.39 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | KLK3 | P07288 | 1/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | USP7 | Q93009 | 1/20 | 0.38 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.37 |
| ▸ | CDK9 | P50750 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14951105 | 0.80 | KDM4E (0.48) | ALDH1A1SMN1; SMN2POLBHPGDNR4A1 | |
| SCHEMBL481771 | 0.79 | ALOX5AP (0.51) | FYNUSP7 | |
| SCHEMBL25619237 | 0.79 | ALOX5AP (0.39) | FYNALDH1A1SMN1; SMN2 | |
| SCHEMBL8940819 | 0.77 | HDAC4 (0.50) | FYNALDH1A1SMN1; SMN2POLBHPGD | |
| SCHEMBL21095840 | 0.77 | ALDH1A1 (0.44) | FYNATMALDH1A1SMN1; SMN2POLB | |
| SCHEMBL21030426 | 0.76 | NPC1 (0.42) | SMN1; SMN2 | |
| SCHEMBL27316386 | 0.75 | SMN1; SMN2 (0.51) | FYNALDH1A1SMN1; SMN2POLBHPGD | |
| SCHEMBL3925174 | 0.75 | CASR (0.48) | FYNALDH1A1SMN1; SMN2HPGDCHEK1 | |
| SCHEMBL3921631 | 0.75 | CASR (0.48) | ALDH1A1NPSR1CHEK1MAPT | |
| SCHEMBL30636365 | 0.74 | HSD17B10 (0.55) | FYNALDH1A1SMN1; SMN2POLBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108368494-A | Methods, compositions and uses of novel FYN kinase inhibitors | 沃伦·C·刘 | 2018-08-03 | — | — | CN | claimed |
| CN-108368494-A | Methods, compositions and uses of novel FYN kinase inhibitors | 沃伦·C·刘 | 2018-08-03 | — | — | CN | disclosed |