Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | USP7 | Q93009 | 2/20 | 0.45 |
| ▸ | FYN | P06241 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ERN1 | O75460 | 1/20 | 0.42 |
| ▸ | CETP | P11597 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CASR | P41180 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9258765 | 0.88 | ERN1 (0.53) | HDAC4HDAC8LMNAFYNERN1 | |
| SCHEMBL14417433 | 0.86 | LMNA (0.56) | HDAC4HDAC8LMNAALDH1A1TRPA1 | |
| SCHEMBL11951612 | 0.85 | CASR (0.53) | HDAC4HDAC8FYNALDH1A1MEN1 | |
| SCHEMBL397150 | 0.84 | ALDH1A1 (0.44) | HDAC4HDAC8ALDH1A1PTGS1SMN1; SMN2 | |
| SCHEMBL84033 | 0.84 | PPARG (0.53) | HDAC4HDAC8LMNAALDH1A1KMT2A | |
| SCHEMBL18084776 | 0.83 | CASR (0.46) | HDAC4HDAC8LMNAFYNERN1 | |
| SCHEMBL16712942 | 0.83 | BACE1 (0.46) | HDAC4HDAC8FYNALDH1A1MEN1 | |
| SCHEMBL16712950 | 0.82 | CTSA (0.48) | HDAC4HDAC8FYNERN1CETP | |
| SCHEMBL16712954 | 0.82 | ERN1 (0.51) | FYNTRPA1PTGS1CACNA1CERN1 | |
| SCHEMBL27316386 | 0.82 | SMN1; SMN2 (0.51) | FYNALDH1A1SMN1; SMN2POLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0700384-A1 | PROCESS FOR PREPARING AND RESOLVING 2-PHENYL-3-AMINOPIPERIDINE | PFIZER (US) | 1996-03-13 | — | — | EP | disclosed |
| WO-1994027966-A1 | PROCESS FOR PREPARING AND RESOLVING 2-PHENYL-3-AMINOPIPERIDINE | PFIZER INC. (US) | 1994-12-08 | — | — | WO | disclosed |
| EP-0581777-A1 | STEREOSELECTIVE PREPARATION OF SUBSTITUTED PIPERIDINES | PFIZER INC. (US) | 1994-02-09 | — | — | EP | disclosed |
| WO-1992017449-A1 | STEREOSELECTIVE PREPARATION OF SUBSTITUTED PIPERIDINES | PFIZER INC. (US) | 1992-10-15 | — | — | WO | disclosed |