Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | USP2 | O75604 | 3/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | RECQL | P46063 | 3/20 | 0.51 |
| ▸ | PKM | P14618 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | BLM | P54132 | 2/20 | 0.51 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | RGS12 | O14924 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | CASP1 | P29466 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1700767 | 0.95 | KDM4E (0.56) | HIF1AKDM4EUSP2TDP1MAPT | |
| SCHEMBL29540097 | 0.95 | KDM4E (0.56) | HIF1AKDM4EUSP2TDP1MAPT | |
| SCHEMBL157790 | 0.95 | KDM4E (0.56) | HIF1AKDM4EUSP2TDP1MAPT | |
| Catechol SCHEMBL28214736 | 0.92 | SLC7A5 (0.53) | HIF1AKDM4EUSP2TDP1MAPT | |
| Phosphoric Acid SCHEMBL28045536 | 0.89 | HIF1A (0.50) | HIF1AKDM4EUSP2TDP1MAPT | |
| SCHEMBL2033390 | 0.82 | NOS3 (0.51) | HIF1AKDM4EUSP2TDP1MAPT | |
| SCHEMBL2031548 | 0.82 | NOS3 (0.51) | HIF1AKDM4EUSP2TDP1MAPT | |
| SCHEMBL2032640 | 0.82 | NOS3 (0.51) | HIF1AKDM4EUSP2TDP1MAPT | |
| SCHEMBL30883294 | 0.81 | IAPP (0.46) | HIF1AKDM4EUSP2TDP1MAPT | |
| SCHEMBL13537519 | 0.81 | SLC7A5 (0.60) | HIF1AKDM4EUSP2TDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102274517-B | The method for treating Parkinson's disease | 纽朗制药公司 | 2018-08-31 | — | — | CN | disclosed |