Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IAPP | P10997 | 4/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | NOS3 | P29474 | 2/20 | 0.41 |
| ▸ | NOS1 | P29475 | 2/20 | 0.41 |
| ▸ | NOS2 | P35228 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | RGS12 | O14924 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL157790 | 0.86 | KDM4E (0.56) | IAPPNOS3NOS1NOS2TDP1 | |
| SCHEMBL1700767 | 0.86 | KDM4E (0.56) | IAPPNOS3NOS1NOS2TDP1 | |
| SCHEMBL29540097 | 0.86 | KDM4E (0.56) | IAPPNOS3NOS1NOS2TDP1 | |
| Catechol SCHEMBL28214736 | 0.83 | SLC7A5 (0.53) | IAPPNOS3NOS1NOS2TDP1 | |
| Chloromethane SCHEMBL28239479 | 0.81 | HIF1A (0.51) | IAPPNOS3NOS1NOS2TDP1 | |
| Phosphoric Acid SCHEMBL28045536 | 0.80 | HIF1A (0.50) | NOS3NOS1NOS2TDP1USP2 | |
| SCHEMBL5463179 | 0.77 | GABRA1 (0.47) | IAPPGABRA1GABRB2TDP1ALOX15 | |
| SCHEMBL632694 | 0.76 | GABRA1 (0.55) | GABRA1GABRB2 | |
| SCHEMBL490685 | 0.76 | KMT2A (0.52) | IAPPGABRA1GABRB2TDP1ALOX15 | |
| SCHEMBL4350641 | 0.75 | IAPP (0.48) | IAPPTDP1HSD17B10ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111868071-B | Novel dopamine precursors | 耶路撒冷希伯来大学伊森姆研究发展有限公司 | 2024-03-26 | — | — | CN | disclosed |