Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | FPR2 | P25090 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2498573 | 0.81 | PIK3C3 (0.32) | — | |
| SCHEMBL5154842 | 0.77 | EPHX2 (0.42) | — | |
| SCHEMBL5160186 | 0.77 | EPHX2 (0.42) | — | |
| SCHEMBL28178861 | 0.76 | DPP4 (0.33) | MAOBFPR2SCN9AMAOA | |
| SCHEMBL28203357 | 0.73 | FPR2 (0.34) | FPR2SCN9A | |
| SCHEMBL15129829 | 0.71 | CNR2 (0.35) | MAOBMAOA | |
| SCHEMBL14829350 | 0.71 | BACE1 (0.39) | — | |
| SCHEMBL30471205 | 0.70 | MAOB (0.34) | MAOBMAOA | |
| SCHEMBL14839832 | 0.69 | CYP2C19 (0.37) | — | |
| SCHEMBL20054334 | 0.69 | MAOB (0.41) | MAOBFPR2SCN9AMAOACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104650070-B | Dihydropyrimidines and its application in drug | 广东东阳光药业有限公司 | 2018-09-14 | — | — | CN | disclosed |