SCHEMBL28239651

SCHEMBL28239651

COC(=O)CNC(=O)c1nc(C)c2cc(OCc3ccccc3)ccc2c1O

nearest known ligand 0.64

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
THRA P10827 13/20 0.64
THRB P10828 13/20 0.64
EGLN1 Q9GZT9 8/20 0.64
BBOX1 O75936 1/20 0.64
SLC6A2 P23975 1/20 0.64
SLC6A3 Q01959 1/20 0.64
ASPH Q12797 1/20 0.64
KDM8 Q8N371 1/20 0.64
FTO Q9C0B1 1/20 0.64
EGLN2 Q96KS0 3/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31028948 0.89 THRA (0.64) THRATHRBEGLN1BBOX1SLC6A2
SCHEMBL522875 0.89 THRA (0.64) THRATHRBEGLN1BBOX1SLC6A2
SCHEMBL30751026 0.87 THRA (0.84) THRATHRBEGLN1BBOX1SLC6A2
SCHEMBL14672081 0.87 THRA (0.84) THRATHRBEGLN1BBOX1SLC6A2
SCHEMBL3783365 0.86 THRA (0.83) THRATHRBEGLN1BBOX1SLC6A2
SCHEMBL20040007 0.84 THRA (0.76) THRATHRBEGLN1BBOX1SLC6A2
SCHEMBL28239618 0.84 EGLN1 (0.54) THRATHRBEGLN1BBOX1SLC6A2
SCHEMBL28240562 0.82 EGLN1 (0.52) THRATHRBEGLN1BBOX1SLC6A2
SCHEMBL25669452 0.82 EGLN1 (0.58) THRATHRBEGLN1BBOX1SLC6A2
SCHEMBL4081493 0.81 THRA (0.56) THRATHRBEGLN1BBOX1SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108383787-A The preparation method of Nuo get Si Ta 王兆举 2018-08-10 CN claimed
CN-108383787-A The preparation method of Nuo get Si Ta 王兆举 2018-08-10 CN disclosed