Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28456624 | 0.84 | TP53 (0.32) | TP53 | |
| SCHEMBL5604362 | 0.82 | TP53 (0.40) | TP53SLC7A5MAPT | |
| SCHEMBL1059263 | 0.75 | LMNA (0.32) | TP53MAPT | |
| SCHEMBL27637884 | 0.74 | TP53 (0.50) | TP53SLC7A5MAPT | |
| SCHEMBL426441 | 0.73 | — | — | |
| Hydrogen Peroxide SCHEMBL374975 | 0.73 | TP53 (0.47) | TP53SLC7A5 | |
| Hydrochloric Acid SCHEMBL7501860 | 0.73 | TSHR (0.30) | — | |
| SCHEMBL800702 | 0.71 | — | — | |
| SCHEMBL19296380 | 0.71 | — | — | |
| SCHEMBL19303439 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106008362-B | A kind of preparation method of pyrimidine derivatives | 杰达维（上海）医药科技发展有限公司 | 2018-08-10 | — | — | CN | claimed |