Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.30 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.30 |
| ▸ | F2 | P00734 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.30 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.30 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7501860 | 0.97 | TSHR (0.30) | LMNAALDH1A1TSHRTHRBRECQL | |
| SCHEMBL426441 | 0.78 | — | — | |
| SCHEMBL28239756 | 0.75 | TP53 (0.40) | TP53MAPT | |
| SCHEMBL5604362 | 0.75 | TP53 (0.40) | TP53MAPT | |
| SCHEMBL4478382 | 0.75 | LMNA (0.42) | LMNAALDH1A1 | |
| SCHEMBL28449695 | 0.74 | — | — | |
| SCHEMBL27787066 | 0.74 | — | — | |
| SCHEMBL104463 | 0.73 | — | — | |
| SCHEMBL891416 | 0.73 | — | — | |
| SCHEMBL27541122 | 0.73 | ALDH1A1 (0.43) | LMNAALDH1A1TSHRTHRBRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 231 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118125918-A | Continuous synthesis method and synthesis device of 4, 4-trifluoro acetoacetic acid ethyl ester | 淄博飞源化工有限公司 | 2024-06-04 | — | — | CN | claimed |
| CN-117843480-A | Synthesis method of 4, 4-trifluoro acetoacetic acid ethyl ester and adopted synthesis device | 淄博飞源化工有限公司 | 2024-04-09 | — | — | CN | claimed |
| CN-117794897-A | Novel process for producing pyribenzoxim using novel intermediates | 安道麦阿甘有限公司 | 2024-03-29 | — | — | CN | claimed |
| CN-117142954-A | Preparation method of ethyl 4, 4-trifluoroacetoacetate | 淄博飞源化工有限公司 | 2023-12-01 | — | — | CN | claimed |
| EP-3486241-B1 | METHOD FOR PRODUCING CRYSTAL OF URACIL COMPOUND | SUMITOMO CHEMICAL CO (JP) | 2022-05-04 | — | — | EP | claimed |
| CN-114195714-A | Simple synthesis method of celecoxib | 山东铂源药业有限公司 | 2022-03-18 | — | — | CN | claimed |
| CN-106905153-B | Method for preparing 2-chloro-4,4, 4-trifluoroacetylacetic acid ethyl ester by continuous non-catalytic reaction | 浙江蓝天环保高科技股份有限公司 | 2020-08-18 | — | — | CN | claimed |
| EP-1812336-B1 | PREPARATION METHOD OF MAGNETIC AND METAL OXIDE NANOPARTICLES | UNIV YONSEI IACF (KR) | 2015-11-11 | — | — | EP | claimed |
| US-6893861-B1 | Method for producing trifluoro-3(r)-hydroxybutyric acid derivatives | LONZA AG (CH) | 2005-05-17 | — | — | US | claimed |
| US-20040082043-A1 | Enzymatic process for the preparation of optically active alcohols from ketones using tuberous root daucus carota | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2004-04-29 | — | — | US | claimed |
| EP-0448544-B1 | Process for preparation of fluoromethyl-substituted piperidine carbodithioates | ROHM & HAAS (US) | 1996-07-03 | — | — | EP | claimed |
| EP-0546669-B1 | Preparation of fluorine-doped tungstic oxide and glass coating process | FORD MOTOR CO (GB) | 1996-04-17 | — | — | EP | claimed |
| EP-0599036-A1 | Method for the preparation of 2-aryl-5-trifluoromethyl pyrrole compounds | AMERICAN CYANAMID COMPANY (US) | 1994-06-01 | — | — | EP | claimed |
| EP-0448544-A2 | Process for preparation of fluoromethyl-substituted piperidine carbodithioates | ROHM AND HAAS COMPANY (US) | 1991-09-25 | — | — | EP | claimed |
| US-5039753-A | Polymers comprising betadiketone groups and polymerizable compositions containing said polymers | LOCTITE (IRELAND) LTD (IE) | 1991-08-13 | — | — | US | claimed |
| EP-0313387-A2 | Polymers comprising betadiketone groups and polymerizable compositions containing said polymers | LOCTITE (IRELAND) Ltd. (IE) | 1989-04-26 | — | — | EP | claimed |
| EP-0135491-B1 | HERBICIDAL 2,6-BIS-FLUOROMETHYL-DIHYDROPYRIDINE-3,5-DICARBOXYLIC ACID ESTERS | MONSANTO COMPANY (US) | 1989-01-25 | — | — | EP | claimed |
| EP-0158399-B1 | LIQUID COATING COMPOSITION FOR PRODUCING HIGH QUALITY, HIGH PERFORMANCE FLUORINE-DOPED TIN OXIDE COATINGS | M & T CHEMICALS, INC. (US) | 1988-11-02 | — | — | EP | claimed |
| EP-0206953-B1 | PROCESS FOR THE PREPARATION OF ETHYL TRIFLUOROACETOACETATE | RHONE-POULENC CHIMIE (FR) | 1988-09-07 | — | — | EP | claimed |
| EP-0206953-A1 | Process for the preparation of ethyl trifluoroacetoacetate | RHONE-POULENC CHIMIE (FR) | 1986-12-30 | — | — | EP | claimed |