SCHEMBL28239791

SCHEMBL28239791

CC(=O)CCc1ccc(Cc2ccc(N3CCOCC3)cc2)cc1

nearest known ligand 0.54

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.54
SLC13A5 Q86YT5 1/20 0.50
FKBP1A P62942 3/20 0.47
PRKDC P78527 1/20 0.47
GSK3B P49841 1/20 0.47
ACACB O00763 1/20 0.46
L3MBTL1 Q9Y468 2/20 0.45
LMNA P02545 2/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
ALDH1A1 P00352 2/20 0.45
POLB P06746 2/20 0.44
CTDSP1 Q9GZU7 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
ITGB3 P05106 1/20 0.44
ITGA2B P08514 1/20 0.44
GAA P10253 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2330058 0.95 MAPT (0.57) MAPTSLC13A5FKBP1APRKDCGSK3B
SCHEMBL27989630 0.83 MAPT (0.59) MAPTSLC13A5FKBP1AGSK3BL3MBTL1
SCHEMBL7530628 0.81 LMNA (0.62) MAPTSLC13A5FKBP1AGSK3BL3MBTL1
SCHEMBL28299497 0.81 MAPT (0.55) MAPTSLC13A5FKBP1AGSK3BL3MBTL1
SCHEMBL11194026 0.80 MAPT (0.56) MAPTSLC13A5PRKDCGSK3BACACB
SCHEMBL27777322 0.78 MAPT (0.58) MAPTSLC13A5FKBP1APRKDCGSK3B
SCHEMBL7618937 0.77 MAPT (0.52) MAPTSLC13A5FKBP1AGSK3BL3MBTL1
SCHEMBL28324747 0.77 MAPT (0.53) MAPTSLC13A5PRKDCGSK3BACACB
SCHEMBL28168696 0.77 MAPT (0.50) MAPTSLC13A5PRKDCGSK3BACACB
SCHEMBL5790255 0.76 PRKDC (0.54) MAPTSLC13A5PRKDCGSK3BL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109880024-A A kind of stereolithography apparatus 3D printing hydrogel and preparation method thereof 西安工业大学 2019-06-14 CN disclosed
CN-109016912-A A kind of endowed processing method of glass surface ink of weather-proof, resistance to wiping 上海银玛标识股份有限公司 2018-12-18 CN disclosed
CN-104945821-B Light-cured resin and preparation method thereof 大族激光科技产业集团股份有限公司 2018-08-10 CN disclosed