Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKDC | P78527 | 2/20 | 0.54 |
| ▸ | ESR1 | P03372 | 2/20 | 0.52 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.52 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.49 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.49 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.49 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.49 |
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
| ▸ | DRD4 | P21917 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2478090 | 0.88 | PRKDC (0.58) | PRKDCESR1ESR2PIK3CDPIK3CA | |
| SCHEMBL5791945 | 0.83 | LMNA (0.64) | PRKDCPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL6373750 | 0.82 | VCP (0.56) | PRKDCESR1ESR2PIK3CDPIK3CA | |
| SCHEMBL4689823 | 0.81 | ALDH1A1 (0.52) | ESR2PIK3CAGSK3BALDH1A1KDM4E | |
| SCHEMBL11504798 | 0.81 | ALDH1A1 (0.46) | PRKDCPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL28121639 | 0.80 | ALDH1A1 (0.46) | PRKDCPIK3CDPIK3CAPIK3CBPIK3CG | |
| Oxirane SCHEMBL4884714 | 0.80 | ESR1 (0.74) | ESR1ESR2GSK3BALDH1A1KDM4E | |
| SCHEMBL1716021 | 0.79 | CHKA (0.56) | PIK3CAPIK3CGGSK3BALDH1A1KDM4E | |
| SCHEMBL8977928 | 0.78 | VCP (0.63) | PRKDCALDH1A1KDM4EMAPTMEN1 | |
| SCHEMBL19831124 | 0.78 | MAPT (0.56) | PRKDCESR1ESR2PIK3CDPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006012683-A1 | CHEMICAL PROCESSES AND COMPOUNDS DERIVED THEREFROM | MONASH UNIVERSITY (AU) | 2006-02-09 | — | — | WO | claimed |