Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.85 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.85 |
| ▸ | NPC1 | O15118 | 7/20 | 0.85 |
| ▸ | MAPT | P10636 | 5/20 | 0.85 |
| ▸ | MEN1 | O00255 | 5/20 | 0.85 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.85 |
| ▸ | TP53 | P04637 | 2/20 | 0.85 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.85 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.85 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.85 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.85 |
| ▸ | LMNA | P02545 | 4/20 | 0.78 |
| ▸ | TSHR | P16473 | 2/20 | 0.78 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.73 |
| ▸ | STAT1 | P42224 | 1/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | NPY5R | Q15761 | 10/20 | 0.60 |
| ▸ | GFER | P55789 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6582639 | 0.88 | RAB9A (1.00) | RAB9ASMN1; SMN2NPC1MAPTMEN1 | |
| SCHEMBL28241488 | 0.85 | SMN1; SMN2 (0.74) | RAB9ASMN1; SMN2NPC1MAPTMEN1 | |
| SCHEMBL28906662 | 0.85 | RAB9A (1.00) | RAB9ASMN1; SMN2NPC1MAPTMEN1 | |
| SCHEMBL1143708 | 0.84 | RAB9A (1.00) | RAB9ASMN1; SMN2NPC1MAPTMEN1 | |
| SCHEMBL28519664 | 0.84 | SMN1; SMN2 (0.67) | RAB9ASMN1; SMN2NPC1MAPTMEN1 | |
| SCHEMBL28241539 | 0.79 | SMN1; SMN2 (0.55) | RAB9ASMN1; SMN2NPC1MAPTMEN1 | |
| SCHEMBL6582516 | 0.79 | NPY5R (0.76) | RAB9ASMN1; SMN2NPC1MAPTMEN1 | |
| SCHEMBL11748979 | 0.77 | CYP1A2 (0.68) | RAB9ASMN1; SMN2NPC1MAPTMEN1 | |
| SCHEMBL28240672 | 0.77 | MAPT (0.79) | RAB9ASMN1; SMN2NPC1MAPTMEN1 | |
| SCHEMBL31324278 | 0.76 | SMN1; SMN2 (0.84) | RAB9ASMN1; SMN2NPC1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108473481-A | compounds useful as kinase inhibitors | 洛克索肿瘤学股份有限公司 | 2018-08-31 | — | — | CN | disclosed |