Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.49 |
| ▸ | ADRB3 | P13945 | 4/20 | 0.49 |
| ▸ | PPARA | Q07869 | 2/20 | 0.47 |
| ▸ | CASR | P41180 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CTSS | P25774 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28921831 | 1.00 | CA1 (0.52) | CA1CA2CA7CA9ADRB2 | |
| SCHEMBL4442846 | 0.81 | KMT2A (0.60) | CA1CA2CA9MAPK1CTSS | |
| SCHEMBL16250356 | 0.80 | ALDH1A1 (0.61) | CA1CA2CA7CA9MAPK1 | |
| SCHEMBL28630691 | 0.79 | ADRB2 (0.41) | ADRB2ADRB1ADRB3SMN1; SMN2 | |
| SCHEMBL16248453 | 0.79 | CA1 (0.57) | CA1CA2CA7CA9MAPK1 | |
| SCHEMBL28763879 | 0.77 | PPARA (0.46) | CA1CA2CA7CA9PPARA | |
| SCHEMBL28533077 | 0.77 | PPARA (0.46) | CA1CA2CA7CA9PPARA | |
| SCHEMBL14721368 | 0.77 | MEN1 (0.48) | ADRB2ADRB1ADRB3CTSSKMT2A | |
| SCHEMBL397022 | 0.77 | CA1 (0.78) | CA1CA2CA7CA9MAPK1 | |
| SCHEMBL28625596 | 0.77 | CA1 (0.58) | CA1CA2CA7CA9MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108473497-A | Ep4 antagonists | 卫材R&D 管理有限公司 | 2018-08-31 | — | — | CN | disclosed |