Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | APAF1 | O14727 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28241093 | 0.98 | — | — | |
| SCHEMBL28241090 | 0.92 | — | — | |
| Bromide SCHEMBL28977717 | 0.83 | MEN1 (0.33) | MEN1APAF1NPC1PLA2G1BHSP90AA1 | |
| SCHEMBL29217939 | 0.81 | MEN1 (0.30) | MEN1APAF1NPC1PLA2G1BHSP90AA1 | |
| SCHEMBL22313650 | 0.81 | MEN1 (0.31) | MEN1APAF1NPC1PLA2G1BHSP90AA1 | |
| Bromide SCHEMBL28399586 | 0.80 | MEN1 (0.41) | MEN1APAF1NPC1PLA2G1BHSP90AA1 | |
| SCHEMBL18155009 | 0.78 | MEN1 (0.38) | MEN1APAF1NPC1PLA2G1BHSP90AA1 | |
| Bromide SCHEMBL20558747 | 0.78 | MEN1 (0.46) | MEN1APAF1NPC1PLA2G1BHSP90AA1 | |
| SCHEMBL28921426 | 0.78 | ALDH1A1 (0.36) | MEN1HSP90AA1KMT2ASMN1; SMN2 | |
| Bromide SCHEMBL30788 | 0.77 | MEN1 (0.50) | MEN1APAF1NPC1PLA2G1BHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106898813-B | Solid electrolyte, solid electrolyte membrane and manufacturing method thereof, and lithium secondary battery | 上海交通大学 | 2020-07-31 | — | — | CN | disclosed |
| CN-108475819-A | Solid electrolyte, solid electrolyte membrane and method for producing same, and secondary battery | 上海交通大学 | 2018-08-31 | — | — | CN | disclosed |