Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | APAF1 | O14727 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.50 |
| ▸ | FDPS | P14324 | 16/20 | 0.38 |
| ▸ | PON1 | P27169 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29389 | 0.98 | MEN1 (0.47) | MEN1HSP90AA1KMT2ASMN1; SMN2APAF1 | |
| Methyl Alcohol SCHEMBL28366592 | 0.97 | MEN1 (0.47) | MEN1HSP90AA1KMT2ASMN1; SMN2APAF1 | |
| Water SCHEMBL28864305 | 0.96 | MEN1 (0.46) | MEN1HSP90AA1KMT2ASMN1; SMN2APAF1 | |
| Hydrochloric Acid SCHEMBL3692896 | 0.96 | MEN1 (0.46) | MEN1HSP90AA1KMT2ASMN1; SMN2APAF1 | |
| Iodide SCHEMBL29164379 | 0.96 | MEN1 (0.46) | MEN1HSP90AA1KMT2ASMN1; SMN2APAF1 | |
| Bromide SCHEMBL29031620 | 0.95 | MEN1 (0.57) | MEN1HSP90AA1KMT2ASMN1; SMN2APAF1 | |
| Bromide SCHEMBL2395867 | 0.93 | MEN1 (0.60) | MEN1HSP90AA1KMT2ASMN1; SMN2APAF1 | |
| Bromide SCHEMBL2395819 | 0.93 | MEN1 (0.60) | MEN1HSP90AA1KMT2ASMN1; SMN2APAF1 | |
| Bromide SCHEMBL2395709 | 0.93 | MEN1 (0.60) | MEN1HSP90AA1KMT2ASMN1; SMN2APAF1 | |
| Bromide SCHEMBL2399324 | 0.93 | MEN1 (0.60) | MEN1HSP90AA1KMT2ASMN1; SMN2APAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 174 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12609352-B2 | Emulsion, emulsion gel electrolyte, aerogel, as well as preparation method and use | SHANDONG UNIVERSITY (CN) | 2026-04-21 | — | — | US | claimed |
| CN-119930916-A | POM-based ionic hydrogel with sensing, fluorescence and antibacterial properties and multifunctional stimulus response, preparation method and application thereof | 河南大学 | 2025-05-06 | — | — | CN | claimed |
| CN-116087289-B | Molecular imprinting miniature electrochemical biosensor for detecting spike protein of novel coronavirus and preparation method and application thereof | 常州大学 | 2025-04-25 | — | — | CN | claimed |
| US-20250043171-A1 | POLYMERIC GELS WITH ORGANIC CROSSLINKERS FOR WATER BLOCKING IN OIL WELLS AND THEIR SYNTHESIS PROCESS | INSTITUTO MEXICANO DEL PETRÓLEO (MX) | 2025-02-06 | — | — | US | claimed |
| CN-118852532-A | Ionic liquid grafted modified starch filtrate reducer and preparation method and application thereof | 中国石油天然气集团有限公司 | 2024-10-29 | — | — | CN | claimed |
| CN-118738599-A | Electrolyte of local high-concentration ionic liquid, preparation method of electrolyte and assembled zinc tellurium battery with high voltage | 广东工业大学 | 2024-10-01 | — | — | CN | claimed |
| US-20240322230-A1 | EMULSION, EMULSION GEL ELECTROLYTE, AEROGEL, AS WELL AS PREPARATION METHOD AND USE | SHANDONG UNIVERSITY (CN) | 2024-09-26 | — | — | US | claimed |
| US-20230339837-A1 | CONSTRUCTION METHOD AND APPLICATION OF MICROTUBE-BASED IONIC LIQUID COLLOID/WATER INTERFACE | EAST CHINA NORMAL UNIVERSITY (CN) | 2023-10-26 | — | — | US | claimed |
| CN-116565345-A | Hydrogel electrolyte with negative poisson ratio structure, preparation method thereof and soft package battery | 哈尔滨工业大学（深圳） | 2023-08-08 | — | — | CN | claimed |
| CN-116087289-A | Molecular imprinting miniature electrochemical biosensor for detecting spike protein of novel coronavirus and preparation method and application thereof | 常州大学 | 2023-05-09 | — | — | CN | claimed |
| CN-112708275-A | Preparation method of hybrid flame retardant for bismaleimide resin | 广西龙酉商贸有限公司 | 2021-04-27 | — | — | CN | claimed |
| CN-112086564-A | Passivating agent and passivation method thereof and method for preparing semiconductor film | 杭州纤纳光电科技有限公司 | 2020-12-15 | — | — | CN | claimed |
| CN-111875960-A | Anti-freezing viscous flame-retardant conductive polymer gel and preparation method and application thereof | 华北科技学院 | 2020-11-03 | — | — | CN | claimed |
| CN-111811702-A | High-recovery conductive film pressure sensor and preparation method thereof | 无锡康森斯克电子科技有限公司 | 2020-10-23 | — | — | CN | claimed |
| CN-111435705-A | Repairing agent and repairing method thereof and method for preparing photoelectric film | 杭州纤纳光电科技有限公司 | 2020-07-21 | — | — | CN | claimed |
| CN-111285951-A | Lipase/polyion liquid-styrene microsphere/hydrogel catalytic material and preparation method and application thereof | 大连工业大学 | 2020-06-16 | — | — | CN | claimed |
| CN-108456288-B | Thermo-sensitive graphene-based electrochemical modification material and preparation method and application thereof | 辽宁大学 | 2020-06-16 | — | — | CN | claimed |
| CN-109029801-B | Metal nanowire composite film pressure sensor and preparation method thereof | 苏州大学 | 2020-04-28 | — | — | CN | claimed |
| WO-2012027242-A1 | HIGH FLUX MICROFILTRATION MEMBRANES WITH VIRUS AND METAL ION ADSORPTION CAPABILITY FOR LIQUID PURIFICATION | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 2012-03-01 | — | — | WO | claimed |
| US-20100261945-A1 | METHOD OF SEPARATING AROMATIC COMPOUND FROM MIXTURE CONTAINING AROMATIC COMPOUND AND ALIPHATIC COMPOUND | SAMSUNG ENGINEERING CO., LTD. (KR) | 2010-10-14 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12609352-B2 | Emulsion, emulsion gel electrolyte, aerogel, as well as preparation method and use | ELOVL3, ELOVL1, EEF1D | MEN1 4843/4885HSP90AA1 1117/4885KMT2A 4466/4885 |
| US-20230339837-A1 | CONSTRUCTION METHOD AND APPLICATION OF MICROTUBE-BASED IONIC LIQUID COLLOID/WATER INTERFACE | PRKDC, KIF15, TUBA3E | MEN1 1013/4885HSP90AA1 2481/4885KMT2A 2984/4885 |
| US-20100261945-A1 | METHOD OF SEPARATING AROMATIC COMPOUND FROM MIXTURE CONTAINING AROMATIC COMPOUND AND ALIPHATIC COMPOUND | AHR, ALK, PAH | MEN1 1736/4885HSP90AA1 4671/4885KMT2A 574/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.