Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.42 |
| ▸ | MEN1 | O00255 | 7/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.42 |
| ▸ | MASP2 | O00187 | 1/20 | 0.42 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.41 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.41 |
| ▸ | FABP6 | P51161 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.40 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.40 |
| ▸ | NPC1 | O15118 | 5/20 | 0.40 |
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
| ▸ | GAA | P10253 | 5/20 | 0.40 |
| ▸ | GLA | P06280 | 4/20 | 0.40 |
| ▸ | GFER | P55789 | 4/20 | 0.40 |
| ▸ | RECQL | P46063 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28241210 | 0.88 | PLAU (0.57) | PLAUALDH1A1MEN1KMT2AMASP2 | |
| SCHEMBL29449363 | 0.80 | MEN1 (0.57) | PLAUALDH1A1MEN1KMT2AMASP2 | |
| SCHEMBL118057 | 0.80 | MEN1 (0.57) | PLAUALDH1A1MEN1KMT2AMASP2 | |
| SCHEMBL14920005 | 0.78 | HTR3E (0.53) | PLAUALDH1A1MEN1KMT2AMASP2 | |
| Hydrochloric Acid SCHEMBL6621838 | 0.78 | MEN1 (0.55) | PLAUALDH1A1MEN1KMT2AMASP2 | |
| SCHEMBL20485659 | 0.76 | ADORA2A (0.49) | PLAUALDH1A1MEN1KMT2ARXFP1 | |
| SCHEMBL726012 | 0.73 | PLAU (0.72) | PLAUALDH1A1MEN1KMT2AMASP2 | |
| SCHEMBL5678732 | 0.73 | JAK2 (0.55) | ALDH1A1MEN1KMT2AMASP2NUDT1 | |
| SCHEMBL5679139 | 0.73 | ALDH1A1 (0.50) | PLAUALDH1A1MEN1KMT2AMASP2 | |
| SCHEMBL5682985 | 0.73 | BACE1 (0.52) | ALDH1A1MEN1KMT2AMASP2NUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108558770-B | Preparation method of diamino nitrogen-containing aromatic heterocyclic compound | 中国科学院长春应用化学研究所 | 2021-07-23 | — | — | CN | disclosed |
| CN-108558770-A | A kind of preparation method of diamino azaaromatics | 中国科学院长春应用化学研究所 | 2018-09-21 | — | — | CN | disclosed |