Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABHD6 | Q9BV23 | 4/20 | 0.50 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.49 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.45 |
| ▸ | NAMPT | P43490 | 4/20 | 0.45 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.40 |
| ▸ | TRAP1 | Q12931 | 1/20 | 0.40 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3578620 | 0.88 | ABHD6 (0.62) | ABHD6DDB1CRBNMAPK1UCHL1 | |
| SCHEMBL29421757 | 0.88 | ABHD6 (0.62) | ABHD6DDB1CRBNMAPK1UCHL1 | |
| SCHEMBL28242065 | 0.85 | DDB1 (0.49) | ABHD6DDB1CRBNMAPK1UCHL1 | |
| SCHEMBL22096353 | 0.85 | UCHL1 (0.60) | ABHD6DDB1CRBNMAPK1UCHL1 | |
| SCHEMBL28863741 | 0.81 | MAPK1 (0.47) | ABHD6DDB1CRBNMAPK1UCHL1 | |
| SCHEMBL19357888 | 0.80 | DDB1 (0.43) | ABHD6DDB1CRBNMAPK1UCHL1 | |
| SCHEMBL25601626 | 0.80 | DDB1 (0.56) | ABHD6DDB1CRBNMAPK1UCHL1 | |
| SCHEMBL2119725 | 0.80 | ABHD6 (0.65) | ABHD6DDB1CRBNMAPK1UCHL1 | |
| SCHEMBL29421744 | 0.80 | ABHD6 (0.65) | ABHD6DDB1CRBNMAPK1UCHL1 | |
| SCHEMBL14894232 | 0.80 | ABHD6 (0.43) | ABHD6DDB1CRBNMAPK1UCHL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108698992-A | 2- cyano isoindoline derivatives for treating cancer | 特殊治疗有限公司 | 2018-10-23 | — | — | CN | disclosed |