Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.43 |
| ▸ | APLNR | P35414 | 2/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | CPN1 | P15169 | 1/20 | 0.37 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.37 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.36 |
| ▸ | EED | O75530 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | IKBKB | O14920 | 1/20 | 0.34 |
| ▸ | CHUK | O15111 | 1/20 | 0.34 |
| ▸ | SYK | P43405 | 1/20 | 0.33 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3444600 | 1.00 | SCN9A (0.43) | SCN9AAPLNRCHRNB2CHRNA4CHRNB4 | |
| SCHEMBL28863484 | 1.00 | SCN9A (0.43) | SCN9AAPLNRCHRNB2CHRNA4CHRNB4 | |
| SCHEMBL4361686 | 0.89 | SLC6A1 (0.41) | SCN9ACHRNB2CHRNA4MAP2K1HRH4 | |
| SCHEMBL4904229 | 0.89 | SLC6A1 (0.41) | SCN9ACHRNB2CHRNA4MAP2K1HRH4 | |
| SCHEMBL4908632 | 0.89 | SLC6A1 (0.41) | SCN9ACHRNB2CHRNA4MAP2K1HRH4 | |
| SCHEMBL795458 | 0.81 | KDM4E (0.37) | TSHRLMNA | |
| SCHEMBL1710717 | 0.78 | LMNA (0.39) | SCN9ATSHRLMNA | |
| SCHEMBL121125 | 0.78 | LMNA (0.39) | TSHRLMNA | |
| SCHEMBL671201 | 0.77 | TDP1 (0.40) | CPN1CPB2SLC6A1SLC6A11TSHR | |
| SCHEMBL2208804 | 0.77 | LMNA (0.37) | SCN9ATSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108473481-A | compounds useful as kinase inhibitors | 洛克索肿瘤学股份有限公司 | 2018-08-31 | — | — | CN | disclosed |