SCHEMBL28243293

SCHEMBL28243293

CC1(C)CSc2ccccc2N1.[H+]

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.43
CRHBP P24387 1/20 0.42
CRHR2 Q13324 1/20 0.42
MEN1 O00255 7/20 0.40
KMT2A Q03164 7/20 0.40
GAA P10253 7/20 0.40
MAPT P10636 6/20 0.39
TDP1 Q9NUW8 3/20 0.39
ALOX12 P18054 2/20 0.39
POLB P06746 2/20 0.39
CYP3A4 P08684 2/20 0.39
NOX1 Q9Y5S8 2/20 0.39
CYP1A2 P05177 1/20 0.39
BCHE P06276 1/20 0.39
ADORA3 P0DMS8 1/20 0.39
ALOX15 P16050 1/20 0.39
MAOA P21397 1/20 0.39
CNR1 P21554 1/20 0.39
ACHE P22303 1/20 0.39
PTGS1 P23219 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29381975 0.98 ALDH1A1 (0.44) ALDH1A1CRHBPCRHR2MEN1KMT2A
SCHEMBL38579 0.98 ALDH1A1 (0.44) ALDH1A1CRHBPCRHR2MEN1KMT2A
Phenothiazine SCHEMBL28071421 0.77 NOX1 (0.41) ALDH1A1CRHBPCRHR2MEN1KMT2A
SCHEMBL28543448 0.77 MAPT (0.43) ALDH1A1CRHBPCRHR2MEN1KMT2A
SCHEMBL10971922 0.73 KDM4E (0.41) ALDH1A1CRHBPCRHR2MEN1KMT2A
SCHEMBL8024749 0.72 ALDH1A1 (0.46) ALDH1A1MEN1KMT2AGAAMAPT
SCHEMBL10971144 0.68 ESR1 (0.41) ALDH1A1CRHBPCRHR2MAPTALOX12
SCHEMBL9148372 0.68 MAPT (0.37) ALDH1A1CRHBPCRHR2MEN1KMT2A
SCHEMBL1641615 0.67 MEN1 (0.47) ALDH1A1MEN1KMT2AGAAMAPT
SCHEMBL14535299 0.67 MEN1 (0.47) ALDH1A1MEN1KMT2AGAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110536620-A Method for manufacturing articles using foam particles NIKE INNOVATE CV 2019-12-03 CN disclosed
CN-207898025-U Combination vamp and outsole for footwear product 耐克创新有限合伙公司 2018-09-25 CN disclosed