Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | CUL4A | Q13619 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | FABP3 | P05413 | 1/20 | 0.32 |
| ▸ | FABP4 | P15090 | 1/20 | 0.32 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SLC26A6 | Q9BXS9 | 2/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2821641 | 0.91 | ALDH1A1 (0.35) | ALDH1A1L3MBTL1KDM4EFABP3FABP4 | |
| SCHEMBL2821878 | 0.90 | ELANE (0.33) | ALDH1A1L3MBTL1KDM4ESMN1; SMN2RAB9A | |
| SCHEMBL2851123 | 0.88 | KDM4E (0.34) | ALDH1A1L3MBTL1KDM4ESMN1; SMN2CA2 | |
| SCHEMBL2820332 | 0.88 | FABP3 (0.33) | ALDH1A1L3MBTL1KDM4ESMN1; SMN2FABP3 | |
| SCHEMBL2819546 | 0.88 | KDM4E (0.31) | ALDH1A1L3MBTL1KDM4EFABP3FABP4 | |
| SCHEMBL2823475 | 0.83 | USP2 (0.36) | ALDH1A1L3MBTL1KDM4ESMN1; SMN2CA2 | |
| SCHEMBL2820995 | 0.83 | KDM4E (0.32) | ALDH1A1L3MBTL1KDM4ESMN1; SMN2GAA | |
| SCHEMBL2820542 | 0.79 | KDM4E (0.31) | ALDH1A1L3MBTL1KDM4EGAA | |
| SCHEMBL2820343 | 0.79 | ELANE (0.34) | ALDH1A1L3MBTL1KDM4ESMN1; SMN2TSHR | |
| SCHEMBL2822078 | 0.79 | MMP13 (0.37) | ALDH1A1L3MBTL1KDM4EGAARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1386914-B1 | HALOGENATED QUINOLINE DERIVATIVES AND ECTOPARASITE CONTROLLERS | MEIJI SEIKA KAISHA (JP) | 2010-10-27 | — | — | EP | disclosed |