Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.47 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CYP4Z1 | Q86W10 | 4/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | CYP4F11 | Q9HBI6 | 1/20 | 0.42 |
| ▸ | CYP4F12 | Q9HCS2 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28242676 | 0.86 | CYP4Z1 (0.48) | MAPTKMT2AMEN1LMNACYP4Z1 | |
| SCHEMBL13282569 | 0.85 | CA1 (0.54) | MAPTKMT2AMEN1CYP4Z1ALDH1A1 | |
| SCHEMBL28242729 | 0.83 | NPC1 (0.58) | MAPTKMT2AMEN1CYP4Z1ALDH1A1 | |
| SCHEMBL654319 | 0.83 | LMNA (0.50) | MAPTKMT2AMEN1LMNACYP4Z1 | |
| SCHEMBL654318 | 0.83 | LMNA (0.50) | MAPTKMT2AMEN1LMNACYP4Z1 | |
| SCHEMBL13302136 | 0.83 | MAPT (0.48) | MAPTKMT2AMEN1LMNACYP4Z1 | |
| SCHEMBL14040320 | 0.83 | MAPT (0.48) | MAPTKMT2AMEN1LMNACYP4Z1 | |
| SCHEMBL1259691 | 0.82 | KMT2A (0.52) | MAPTKMT2AMEN1LMNANPSR1 | |
| SCHEMBL809447 | 0.82 | KMT2A (0.52) | MAPTKMT2AMEN1LMNANPSR1 | |
| SCHEMBL12528504 | 0.82 | KMT2A (0.52) | MAPTKMT2AMEN1LMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108586404-A | A kind of synthetic method of N- aryl naphtho- furanone imine compound | 湖南大学 | 2018-09-28 | — | — | CN | disclosed |