SCHEMBL28243648

SCHEMBL28243648

CC(=O)OF.NC(F)CF

nearest known ligand 0.31

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.31
TSHR P16473 2/20 0.31
LMNA P02545 1/20 0.31
HSD17B10 Q99714 1/20 0.31
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20508246 0.82 ALDH1A1 (0.32) ALDH1A1TSHRLMNAHSD17B10TDP1
SCHEMBL11294314 0.80 ALDH1A1 (0.31) ALDH1A1TSHRLMNAHSD17B10TDP1
SCHEMBL1008696 0.78
SCHEMBL2226503 0.75
SCHEMBL566286 0.75
SCHEMBL454137 0.74
SCHEMBL14086859 0.74
SCHEMBL2877989 0.73
SCHEMBL3285270 0.71
Fluoride SCHEMBL31481331 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106317043-B A kind of 2 agonist of Cannabined receptor 成都理工大学 2018-11-02 CN disclosed