SCHEMBL28243713

SCHEMBL28243713

O=Cc1cc(Br)cc(-c2nc3ccccc3s2)c1O

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 12/20 0.53
RAB9A P51151 11/20 0.53
KDM4E B2RXH2 11/20 0.53
NPC1 O15118 8/20 0.53
NPSR1 Q6W5P4 2/20 0.53
RXFP1 Q9HBX9 2/20 0.47
MEN1 O00255 8/20 0.47
KMT2A Q03164 8/20 0.47
GAA P10253 7/20 0.47
SMN1; SMN2 Q16637 7/20 0.47
L3MBTL1 Q9Y468 5/20 0.47
POLB P06746 4/20 0.47
HSD17B10 Q99714 3/20 0.47
TDP1 Q9NUW8 2/20 0.47
APP P05067 1/20 0.47
THRB P10828 1/20 0.47
ALOX15 P16050 1/20 0.47
CASP1 P29466 1/20 0.47
SNCA P37840 1/20 0.47
CASP7 P55210 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28339630 0.85 MAPT (0.50) MAPTRAB9AKDM4ENPC1NPSR1
SCHEMBL29578593 0.85 MAPT (0.50) MAPTRAB9AKDM4ENPC1NPSR1
SCHEMBL7197008 0.82 RAB9A (0.60) MAPTRAB9AKDM4ENPC1NPSR1
SCHEMBL30471834 0.82 RAB9A (0.60) MAPTRAB9AKDM4ENPC1NPSR1
SCHEMBL31733941 0.81 RAB9A (0.59) MAPTRAB9AKDM4ENPC1NPSR1
SCHEMBL28590372 0.79 KDM4E (0.58) MAPTRAB9AKDM4ENPC1NPSR1
SCHEMBL23723 0.79 KDM4E (0.58) MAPTRAB9AKDM4ENPC1NPSR1
SCHEMBL27910186 0.78 ERN1 (0.54) MAPTRAB9AKDM4ENPC1NPSR1
SCHEMBL2475992 0.76 KDM4E (0.58) MAPTRAB9AKDM4ENPC1NPSR1
SCHEMBL30834953 0.75 MAPT (0.69) MAPTRAB9AKDM4ENPC1NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108586382-A A kind of schiff base compound and its preparation and the application in copper ion detection 山西大学 2018-09-28 CN claimed
CN-108586382-B Schiff base compound, preparation thereof and application thereof in copper ion detection 山西大学 2021-09-28 CN disclosed
CN-108586382-B Schiff base compound, preparation thereof and application thereof in copper ion detection 山西大学 2021-09-28 CN disclosed
CN-108586382-A A kind of schiff base compound and its preparation and the application in copper ion detection 山西大学 2018-09-28 CN disclosed