SCHEMBL29578593

SCHEMBL29578593

Cc1cc(C=O)c(O)c(-c2nc3ccccc3s2)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 11/20 0.50
RAB9A P51151 7/20 0.50
KDM4E B2RXH2 7/20 0.50
NPC1 O15118 4/20 0.50
NPSR1 Q6W5P4 1/20 0.50
MEN1 O00255 6/20 0.48
KMT2A Q03164 6/20 0.48
SMN1; SMN2 Q16637 5/20 0.48
ALDH1A1 P00352 5/20 0.48
GAA P10253 3/20 0.47
POLB P06746 3/20 0.47
TDP1 Q9NUW8 2/20 0.47
L3MBTL1 Q9Y468 2/20 0.47
HSD17B10 Q99714 2/20 0.47
APP P05067 1/20 0.47
THRB P10828 1/20 0.47
ALOX15 P16050 1/20 0.47
CASP1 P29466 1/20 0.47
SNCA P37840 1/20 0.47
CASP7 P55210 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28339630 1.00 MAPT (0.50) MAPTRAB9AKDM4ENPC1NPSR1
SCHEMBL28243713 0.85 MAPT (0.53) MAPTRAB9AKDM4ENPC1NPSR1
SCHEMBL2788428 0.82 MAPT (0.56) MAPTRAB9AKDM4ENPC1NPSR1
SCHEMBL31733941 0.81 RAB9A (0.59) MAPTRAB9AKDM4ENPC1NPSR1
SCHEMBL28126989 0.80 MAPT (0.51) MAPTRAB9AKDM4ENPC1NPSR1
SCHEMBL29236406 0.79 MAPT (0.40) MAPTRAB9AKDM4ENPC1NPSR1
SCHEMBL23723 0.79 KDM4E (0.58) MAPTRAB9AKDM4ENPC1NPSR1
SCHEMBL28590372 0.79 KDM4E (0.58) MAPTRAB9AKDM4ENPC1NPSR1
SCHEMBL2475992 0.76 KDM4E (0.58) MAPTRAB9AKDM4ENPC1NPSR1
SCHEMBL2790890 0.75 MAPT (0.69) MAPTRAB9AKDM4ENPC1NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117024431-A Dihydrobenzimidazole quinazoline derivative fluorescent probe and preparation method and application thereof 河南理工大学 2023-11-10 CN claimed
CN-114907336-B Zinc ion fluorescent probe based on benzothiazole and preparation method and application thereof 廊坊师范学院 2023-08-29 CN claimed
CN-114907336-A Zinc ion fluorescent probe based on benzothiazole, and preparation method and application thereof 廊坊师范学院 2022-08-16 CN claimed
CN-114634429-A Photosensitive diamine monomer, preparation method thereof, resin containing photosensitive diamine monomer and photosensitive resin composition 波米科技有限公司 2022-06-17 CN claimed
CN-111205243-B Reagent for distinguishing and detecting thiophenol as well as synthesis method and application thereof 山西大学 2022-05-20 CN claimed
CN-118125972-B Diamine monomer with nitrogen heterocycle and benzocyclobutene structure, and preparation method and application thereof 波米科技有限公司 2024-09-20 CN disclosed
CN-118108661-B Diamine monomer with nitrogen heterocycle and benzocyclobutene structure, and preparation method and application thereof 波米科技有限公司 2024-09-20 CN disclosed
CN-118125972-A Diamine monomer with nitrogen heterocycle and benzocyclobutene structure, and preparation method and application thereof 波米科技有限公司 2024-06-04 CN disclosed
CN-118108661-A Diamine monomer with nitrogen heterocycle and benzocyclobutene structure, and preparation method and application thereof 波米科技有限公司 2024-05-31 CN disclosed
CN-117247381-A Hydrogen sulfite and polar fluorescent probe and preparation method and application thereof 郑州大学 2023-12-19 CN disclosed
CN-117024431-A Dihydrobenzimidazole quinazoline derivative fluorescent probe and preparation method and application thereof 河南理工大学 2023-11-10 CN disclosed
CN-114907336-B Zinc ion fluorescent probe based on benzothiazole and preparation method and application thereof 廊坊师范学院 2023-08-29 CN disclosed
CN-114634429-B Photosensitive diamine monomer and preparation method thereof, resin containing photosensitive diamine monomer and photosensitive resin composition 波米科技有限公司 2022-11-22 CN disclosed
CN-114907336-A Zinc ion fluorescent probe based on benzothiazole, and preparation method and application thereof 廊坊师范学院 2022-08-16 CN disclosed
CN-114634429-A Photosensitive diamine monomer, preparation method thereof, resin containing photosensitive diamine monomer and photosensitive resin composition 波米科技有限公司 2022-06-17 CN disclosed
CN-111205243-B Reagent for distinguishing and detecting thiophenol as well as synthesis method and application thereof 山西大学 2022-05-20 CN disclosed