SCHEMBL28243779

SCHEMBL28243779

COc1cc(O)c2c(c1)C(=O)c1cc(O)c(C(=O)O)c(C)c1C2=O

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.63
ALDH1A1 P00352 5/20 0.63
ELANE P08246 4/20 0.63
KDM4E B2RXH2 3/20 0.63
HPGD P15428 3/20 0.63
ALOX15 P16050 2/20 0.63
GLA P06280 1/20 0.63
POLB P06746 4/20 0.57
MAPK1 P28482 4/20 0.57
RECQL P46063 3/20 0.57
GAA P10253 1/20 0.57
G6PD P11413 1/20 0.57
MCL1 Q07820 1/20 0.57
ACLY P53396 2/20 0.47
KMT2A Q03164 4/20 0.47
ACHE P22303 2/20 0.46
CYP3A4 P08684 5/20 0.45
CYP1A2 P05177 2/20 0.45
MEN1 O00255 3/20 0.44
TDP1 Q9NUW8 3/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2138871 0.86 CYP3A4 (0.60) MAPTALDH1A1ELANEKDM4EHPGD
SCHEMBL29356605 0.86 CYP3A4 (0.60) MAPTALDH1A1ELANEKDM4EHPGD
SCHEMBL16226012 0.84 ELANE (0.54) MAPTALDH1A1ELANEKDM4EHPGD
SCHEMBL16226557 0.83 ELANE (0.62) MAPTALDH1A1ELANEKDM4EHPGD
SCHEMBL16226983 0.82 ELANE (0.83) MAPTALDH1A1ELANEKDM4EHPGD
SCHEMBL16225652 0.80 ALDH1A1 (0.69) MAPTALDH1A1ELANEKDM4EHPGD
Physcion SCHEMBL30425832 0.78 ELANE (1.00) MAPTALDH1A1ELANEKDM4EHPGD
Physcion SCHEMBL486155 0.78 ELANE (1.00) MAPTALDH1A1ELANEKDM4EHPGD
Physcion SCHEMBL29404320 0.78 ELANE (1.00) MAPTALDH1A1ELANEKDM4EHPGD
SCHEMBL5142787 0.78 SLC37A4 (0.67) MAPTALDH1A1ELANEKDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108739810-A Application of the anthraquinone analog compound as bioflm inhibiting agents 深圳大学 2018-11-06 CN disclosed