Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.32 |
| ▸ | GRM3 | Q14832 | 2/20 | 0.32 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19919700 | 0.84 | FFAR3 (0.54) | SMN1; SMN2TDP1GAAFFAR3GRM2 | |
| SCHEMBL2232346 | 0.81 | SMN1; SMN2 (0.43) | SMN1; SMN2TDP1GAAKMT2AKDM4E | |
| SCHEMBL20855519 | 0.79 | SMN1; SMN2 (0.40) | SMN1; SMN2TDP1GAAKMT2AMAPT | |
| SCHEMBL16841477 | 0.79 | SMN1; SMN2 (0.42) | SMN1; SMN2TDP1GAAKMT2AKDM4E | |
| SCHEMBL19315873 | 0.79 | SMN1; SMN2 (0.42) | SMN1; SMN2TDP1GAAKMT2AKDM4E | |
| SCHEMBL19706806 | 0.79 | TDP1 (0.35) | SMN1; SMN2TDP1FFAR3PKML3MBTL1 | |
| SCHEMBL16841467 | 0.79 | SMN1; SMN2 (0.42) | SMN1; SMN2TDP1GAAKMT2AKDM4E | |
| SCHEMBL13232149 | 0.79 | SMN1; SMN2 (0.42) | SMN1; SMN2TDP1GAAKMT2AKDM4E | |
| SCHEMBL14738152 | 0.79 | TDP1 (0.35) | SMN1; SMN2TDP1FFAR3PKML3MBTL1 | |
| SCHEMBL14738624 | 0.79 | TDP1 (0.35) | SMN1; SMN2TDP1FFAR3PKML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116916924-A | MALT1 modulators and uses thereof | 稀有生物科学股份有限公司 | 2023-10-20 | — | — | CN | disclosed |
| CN-109665203-A | Tubular package | 旭化成株式会社 | 2019-04-23 | — | — | CN | disclosed |
| CN-108602595-A | Cylindrical molding, barrier property mouth plug and the container with barrier property mouth plug | 旭化成株式会社 | 2018-09-28 | — | — | CN | disclosed |