Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.37 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.36 |
| ▸ | APLNR | P35414 | 2/20 | 0.36 |
| ▸ | GALR1 | P47211 | 1/20 | 0.35 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | RBP4 | P02753 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30088795 | 0.74 | PIK3CD (0.44) | GAATDP1HSD11B1APLNR | |
| SCHEMBL28606349 | 0.73 | KCNH2 (0.44) | GAAKDM4EALDH1A1HSD11B1 | |
| SCHEMBL28846380 | 0.70 | HSD11B1 (0.51) | HSD11B1 | |
| SCHEMBL8250269 | 0.70 | SLC18A3 (0.43) | KDM4EALDH1A1HSD11B1 | |
| SCHEMBL8505690 | 0.70 | PTGES2 (0.37) | ALDH1A1CYP1A2CYP2D6SMN1; SMN2 | |
| SCHEMBL12504926 | 0.68 | GLA (0.39) | — | |
| SCHEMBL8022901 | 0.68 | HSD11B1 (0.54) | TDP1ALDH1A1HSD11B1CYP1A2CYP2D6 | |
| SCHEMBL18939614 | 0.67 | APLNR (0.58) | APLNR | |
| SCHEMBL28598700 | 0.67 | GLA (0.41) | ALDH1A1 | |
| SCHEMBL28918999 | 0.67 | GCGR (0.40) | KDM4EALDH1A1OPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108602806-A | Improved Ai Palin peptides receptor (APJ) agonist and application thereof | 研究三角协会 | 2018-09-28 | — | — | CN | disclosed |