Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR3 | P29371 | 9/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TACR1 | P25103 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17465167 | 0.82 | HCAR2 (0.50) | TACR3MAPTSLC6A4HTTKMT2A | |
| SCHEMBL27666225 | 0.82 | HCAR2 (0.50) | TACR3MAPTSLC6A4HTTKMT2A | |
| SCHEMBL4901518 | 0.78 | LMNA (0.43) | HTTKMT2ALMNA | |
| SCHEMBL28305489 | 0.78 | MAPT (0.45) | TACR3MAPTSLC6A4HTTKMT2A | |
| SCHEMBL17844765 | 0.75 | MAPT (0.43) | TACR3MAPTHTTKMT2AMEN1 | |
| SCHEMBL20482479 | 0.75 | KMT2A (0.48) | TACR3MAPTHTTKMT2AMEN1 | |
| SCHEMBL28862367 | 0.75 | MAPT (0.47) | TACR3MAPTHTTKMT2AMEN1 | |
| SCHEMBL27983615 | 0.75 | MAPT (0.43) | TACR3MAPTHTTKMT2AMEN1 | |
| SCHEMBL28764377 | 0.75 | CYP1A2 (0.44) | KMT2ALMNA | |
| SCHEMBL27485822 | 0.75 | SCN9A (0.47) | TACR3MAPTLMNASCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108617166-A | Protein Kinase Inhibitor Benzolactam Compounds | 大冢制药株式会社 | 2018-10-02 | — | — | CN | disclosed |