SCHEMBL28245197

SCHEMBL28245197

Cc1ccc2c(c1S)C(=O)c1ccccc1C2

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 3/20 0.53
CES1 P23141 2/20 0.46
BCHE P06276 1/20 0.46
ALDH1A1 P00352 6/20 0.44
KMT2A Q03164 3/20 0.41
KDM4E B2RXH2 2/20 0.41
MEN1 O00255 2/20 0.41
CYP1A2 P05177 1/20 0.40
CYP2C19 P33261 1/20 0.40
AKT1 P31749 1/20 0.39
AKT2 P31751 1/20 0.39
AKT3 Q9Y243 1/20 0.39
CYP3A4 P08684 3/20 0.39
TSHR P16473 3/20 0.39
CASP3 P42574 2/20 0.39
SENP7 Q9BQF6 2/20 0.39
SENP6 Q9GZR1 2/20 0.39
L3MBTL1 Q9Y468 2/20 0.39
NPC1 O15118 1/20 0.39
MAPK1 P28482 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9093467 0.83 MAOA (0.57) MAOACES1BCHEALDH1A1KMT2A
SCHEMBL28378453 0.81 MAOA (0.53) MAOACES1BCHEALDH1A1KMT2A
SCHEMBL30177232 0.80 MAOA (0.61) MAOACES1BCHEALDH1A1KMT2A
SCHEMBL4652610 0.80 MAOA (0.61) MAOACES1BCHEALDH1A1KMT2A
SCHEMBL29364462 0.76 MAOA (0.61) MAOACES1BCHEALDH1A1KMT2A
SCHEMBL17796874 0.76 MAOA (0.61) MAOACES1BCHEALDH1A1KMT2A
SCHEMBL11481878 0.75 MAOA (0.50) MAOACES1BCHEALDH1A1KMT2A
SCHEMBL769934 0.75 MAOA (0.71) MAOACES1BCHEALDH1A1KMT2A
Anthrone SCHEMBL11617600 0.75 MAOA (0.78) MAOACES1BCHEALDH1A1KMT2A
SCHEMBL27640285 0.75 MAOA (0.46) MAOACES1BCHEALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104797612-B surface treatment composition 大金工业株式会社 2018-09-11 CN disclosed