Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | IDH1 | O75874 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 2/20 | 0.40 |
| ▸ | CES1 | P23141 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | AKT1 | P31749 | 1/20 | 0.38 |
| ▸ | AKT2 | P31751 | 1/20 | 0.38 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | HBB | P68871 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27640288 | 0.84 | MAOA (0.47) | MAOAMAOBBCHECES1ACHE | |
| SCHEMBL9093467 | 0.77 | MAOA (0.57) | MAOAMAOBBCHECES1ACHE | |
| SCHEMBL27640476 | 0.77 | MAOA (0.52) | MAOAMAOBBCHECES1ACHE | |
| SCHEMBL10517737 | 0.76 | CYP19A1 (0.44) | MAOAMAOBBCHECES1CYP3A4 | |
| SCHEMBL28245197 | 0.75 | MAOA (0.53) | MAOAMAOBBCHECES1ACHE | |
| SCHEMBL4652610 | 0.74 | MAOA (0.61) | MAOAMAOBBCHECES1ACHE | |
| SCHEMBL30177232 | 0.74 | MAOA (0.61) | MAOAMAOBBCHECES1ACHE | |
| SCHEMBL27640284 | 0.72 | MAOA (0.46) | MAOAMAOBBCHECES1ACHE | |
| SCHEMBL28721340 | 0.71 | MAOA (0.52) | MAOAMAOBBCHECES1ACHE | |
| SCHEMBL10756250 | 0.70 | MAOA (0.55) | MAOAMAOBBCHECES1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100509740-C | 10,10-dibenzyl anthrone and derivative and synthetic method thereof | GUANGZHOU INST OF CHEMISTRY (CN) | 2009-07-08 | — | — | CN | disclosed |
| CN-1858033-A | 10,10-dibenzyl anthrone and its derivative and synthetic method | GUANGZHOU INST CHEMISTRY CAS (CN) | 2006-11-08 | — | — | CN | disclosed |