Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH2 | P25021 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28246000 | 0.89 | SMN1; SMN2 (0.35) | SIGMAR1CHRM5CHRM3 | |
| Piperazine SCHEMBL28135603 | 0.81 | — | — | |
| SCHEMBL40708 | 0.75 | — | — | |
| SCHEMBL28181859 | 0.75 | DPP4 (0.31) | — | |
| Pyrrole SCHEMBL28201580 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL31716836 | 0.74 | — | — | |
| Methylamine SCHEMBL928302 | 0.70 | POLB (0.46) | SIGMAR1MEN1KMT2A | |
| SCHEMBL6927442 | 0.70 | — | — | |
| SCHEMBL178388 | 0.70 | — | — | |
| Hydrochloric Acid SCHEMBL1578109 | 0.68 | POLB (0.48) | SIGMAR1LMNACHRM5CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104940202-B | Inhibitors of influenza viruses replication | 沃泰克斯药物股份有限公司 | 2018-10-16 | — | — | CN | disclosed |