Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TYMP | P19971 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 3/20 | 0.35 |
| ▸ | MAOA | P21397 | 2/20 | 0.35 |
| ▸ | PSD | A5PKW4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4172004 | 0.77 | HPGD (0.44) | DAOMEN1KMT2AHPGD | |
| SCHEMBL28245640 | 0.71 | DAO (0.44) | DAOTP53MAPTHTTCTSB | |
| SCHEMBL4163074 | 0.65 | L3MBTL1 (0.50) | DAOHPGD | |
| SCHEMBL22211000 | 0.62 | IDO1 (0.55) | DAOMAPTHTTALDH1A1SMN1; SMN2 | |
| SCHEMBL28180117 | 0.62 | IDO1 (0.59) | DAOMAPTHTTSMN1; SMN2RAB9A | |
| SCHEMBL4597178 | 0.62 | HTT (0.66) | DAOMAPTHTTALDH1A1SMN1; SMN2 | |
| SCHEMBL24215283 | 0.61 | DAO (1.00) | DAOTP53MAPTCTSBSMN1; SMN2 | |
| SCHEMBL4158434 | 0.60 | DAO (0.43) | DAOKMT2A | |
| SCHEMBL595992 | 0.59 | LOXL2 (0.58) | MAPTHTTALDH1A1IDO1MAOB | |
| SCHEMBL8664887 | 0.59 | HTT (0.39) | DAOTP53MAPTHTTCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106146409-B | The preparation method of 2- arylthio -5- halogenated pyrimidine ketones derivants and its application as anti-hepatic-B virus medicine | 北京大学 | 2018-10-12 | — | — | CN | disclosed |