SCHEMBL28246714

SCHEMBL28246714

CCONC(O)=S.NC(O)=S

nearest known ligand 0.31

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.31
CA12 O43570 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA9 Q16790 1/20 0.31
ADRA2A P08913 1/20 0.30
ADRA2B P18089 1/20 0.30
ADRA2C P18825 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3227325 0.78
SCHEMBL9752021 0.71 CA12 (0.36) ALOX15CA12CA1CA2CA9
Ether SCHEMBL6378449 0.71 ALDH1A1 (0.38) ALOX15CA12CA1CA2CA9
SCHEMBL11398785 0.70
SCHEMBL28569140 0.70
Propane SCHEMBL11720454 0.69 TSHR (0.42) ALOX15CA12CA1CA2CA9
Propane SCHEMBL7026177 0.69 TSHR (0.42) ALOX15CA12CA1CA2CA9
Propane SCHEMBL7566447 0.69 TSHR (0.42) ALOX15CA12CA1CA2CA9
SCHEMBL28179418 0.68
SCHEMBL166760 0.67 ALOX15 (0.32) ALOX15ADRA2AADRA2BADRA2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108636613-A A kind of N, N- dialkyl group-S- hydroxyalkyls-dithiocarbamate collector and the preparation method and application thereof 中南大学 2018-10-12 CN disclosed