Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 1.00 |
| ▸ | LMNA | P02545 | 2/20 | 1.00 |
| ▸ | CRHBP | P24387 | 2/20 | 1.00 |
| ▸ | CRHR2 | Q13324 | 2/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 1.00 |
| ▸ | POLB | P06746 | 3/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.55 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7711914 | 0.94 | MAPT (0.88) | MAPTALDH1A1LMNACRHBPCRHR2 | |
| SCHEMBL31203024 | 0.87 | MAPT (0.77) | MAPTALDH1A1LMNACRHBPCRHR2 | |
| SCHEMBL1813611 | 0.86 | MAPT (0.75) | MAPTALDH1A1LMNACRHBPCRHR2 | |
| SCHEMBL31203067 | 0.86 | MAPT (0.75) | MAPTALDH1A1LMNACRHBPCRHR2 | |
| SCHEMBL31203108 | 0.82 | ALDH1A1 (0.69) | MAPTALDH1A1LMNACRHBPCRHR2 | |
| SCHEMBL32685902 | 0.82 | ALDH1A1 (0.69) | MAPTALDH1A1LMNACRHBPCRHR2 | |
| SCHEMBL23786250 | 0.82 | MAPT (0.69) | MAPTALDH1A1LMNACRHBPCRHR2 | |
| SCHEMBL8607686 | 0.82 | MAPT (0.69) | MAPTALDH1A1LMNACRHBPCRHR2 | |
| SCHEMBL7182913 | 0.82 | MAPT (0.69) | MAPTALDH1A1LMNACRHBPCRHR2 | |
| SCHEMBL9396486 | 0.81 | MAPT (0.68) | MAPTALDH1A1LMNACRHBPCRHR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108690043-B | Quinoline derivatives and its preparation method and application | 东莞东阳光科研发有限公司 | 2019-10-18 | — | — | CN | disclosed |
| CN-108690043-A | Quinoline derivatives and its preparation method and application | 东莞东阳光科研发有限公司 | 2018-10-23 | — | — | CN | disclosed |