SCHEMBL28247152

SCHEMBL28247152

c1ccc2cc(Cc3nc[nH]n3)ccc2c1

nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 1/20 0.46
NFKB1 P19838 1/20 0.46
TAAR1 Q96RJ0 1/20 0.46
CNR1 P21554 1/20 0.46
CNR2 P34972 1/20 0.46
CYP1A2 P05177 1/20 0.44
CYP2A6 P11509 1/20 0.44
MPO P05164 1/20 0.43
ADORA2A P29274 1/20 0.43
ADORA1 P30542 1/20 0.43
PDE10A Q9Y233 3/20 0.42
ALOX5 P09917 1/20 0.41
CETP P11597 1/20 0.40
SLC6A2 P23975 1/20 0.40
SLC6A4 P31645 1/20 0.40
SLC6A3 Q01959 1/20 0.40
RAB9A P51151 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL9382673 0.76 TAAR1 (0.46) CYP2D6TAAR1CYP1A2
SCHEMBL2838141 0.74 CYP1A2 (0.65) CYP2D6NFKB1TAAR1CYP1A2CYP2A6
SCHEMBL4948276 0.74 DPYD (0.53) MPOALOX5RAB9A
SCHEMBL31588006 0.72 HTR2C (0.47) TAAR1MPO
SCHEMBL5731861 0.71 LTA4H (0.50) CYP2D6
SCHEMBL2103758 0.71 BACE1 (0.47) CYP2D6NFKB1TAAR1CNR1CNR2
SCHEMBL5900962 0.71 CYP1A2 (0.60) CYP2D6NFKB1TAAR1CYP1A2CYP2A6
SCHEMBL28846677 0.71 CYP1A2 (0.60) CYP2D6NFKB1TAAR1CYP1A2CYP2A6
SCHEMBL3915675 0.71 CYP3A4 (0.50)
SCHEMBL598561 0.69 CYP1A2 (0.58) CYP2D6NFKB1TAAR1CYP1A2CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108689951-A 3-triazole compounds and its application in agricultural 东莞东阳光科研发有限公司 2018-10-23 CN disclosed