SCHEMBL28247335

SCHEMBL28247335

CC(=O)Cc1ccc(N(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.46
TSHR P16473 2/20 0.46
GLA P06280 1/20 0.46
POLB P06746 1/20 0.44
KMT2A Q03164 3/20 0.44
MEN1 O00255 2/20 0.44
CES2 O00748 1/20 0.43
CES1 P23141 1/20 0.43
AKR1B1 P15121 1/20 0.43
LMNA P02545 2/20 0.42
ABCC4 O15439 1/20 0.42
GAA P10253 1/20 0.42
PTGS1 P23219 1/20 0.42
HTT P42858 1/20 0.42
CNR2 P34972 2/20 0.42
KDM4E B2RXH2 1/20 0.42
CYP1A2 P05177 1/20 0.42
CYP3A4 P08684 1/20 0.42
CYP2D6 P10635 1/20 0.42
MAPT P10636 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8642376 0.85 HPGD (0.46) ALDH1A1POLBKMT2AMEN1GAA
SCHEMBL436641 0.84 AKR1B1 (0.64) ALDH1A1TSHRPOLBKMT2AMEN1
Benzene SCHEMBL10503945 0.81 CES1 (0.64) ALDH1A1TSHRPOLBKMT2AMEN1
SCHEMBL1331954 0.81 CES1 (0.64) ALDH1A1TSHRPOLBKMT2AMEN1
Benzene SCHEMBL11066939 0.81 CES1 (0.64) ALDH1A1TSHRPOLBKMT2AMEN1
Benzene SCHEMBL3421936 0.81 CES1 (0.64) ALDH1A1TSHRPOLBKMT2AMEN1
Benzene SCHEMBL7058395 0.81 CES1 (0.64) ALDH1A1TSHRPOLBKMT2AMEN1
Benzene SCHEMBL2333780 0.81 CES1 (0.64) ALDH1A1TSHRPOLBKMT2AMEN1
SCHEMBL9688483 0.81 CES1 (0.64) ALDH1A1TSHRPOLBKMT2AMEN1
Benzene SCHEMBL6698503 0.81 CES1 (0.64) ALDH1A1TSHRPOLBKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109627150-A A method of improving distortion acene compound non-linear absorption performance 哈尔滨工业大学 2019-04-16 CN claimed
CN-109336776-A It is a kind of to replace conjugated compound and its application by the big steric hindrance alkoxy of end group of triaryl amine 衡阳师范学院 2019-02-15 CN claimed
CN-109627150-A A method of improving distortion acene compound non-linear absorption performance 哈尔滨工业大学 2019-04-16 CN disclosed
CN-109438155-A It is conjugated alkynyl anthracene derivative, preparation method and applications 安庆北化大科技园有限公司 2019-03-08 CN disclosed
CN-109336776-A It is a kind of to replace conjugated compound and its application by the big steric hindrance alkoxy of end group of triaryl amine 衡阳师范学院 2019-02-15 CN disclosed
CN-108699019-A Benzofuran derivatives useful in the treatment of central nervous system and other diseases 华纳巴布科克绿色化学学院有限公司 2018-10-23 CN disclosed