Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 2/20 | 0.54 |
| ▸ | LCK | P06239 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA7 | P43166 | 1/20 | 0.49 |
| ▸ | XDH | P47989 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29365729 | 0.85 | PTPN11 (0.68) | PTPN11LCKALDH1A1SMN1; SMN2ATM | |
| SCHEMBL69025 | 0.85 | PTPN11 (0.68) | PTPN11LCKALDH1A1SMN1; SMN2ATM | |
| SCHEMBL8732524 | 0.83 | PTPN11 (0.66) | PTPN11LCKALDH1A1SMN1; SMN2ATM | |
| SCHEMBL9979782 | 0.81 | PTPN11 (0.64) | PTPN11LCKALDH1A1SMN1; SMN2ATM | |
| SCHEMBL18466692 | 0.80 | PTPN11 (0.58) | PTPN11LCKALDH1A1SMN1; SMN2ATM | |
| SCHEMBL264087 | 0.80 | PTPN11 (0.51) | PTPN11LCKALDH1A1SMN1; SMN2ATM | |
| SCHEMBL709231 | 0.79 | LCK (0.62) | PTPN11LCKALDH1A1SMN1; SMN2ATM | |
| SCHEMBL264052 | 0.78 | PTPN11 (0.60) | PTPN11LCKALDH1A1SMN1; SMN2ATM | |
| SCHEMBL7744907 | 0.78 | PTPN11 (0.65) | PTPN11LCKCA1CA2CA12 | |
| SCHEMBL13900228 | 0.78 | CYP11B1 (0.69) | PTPN11LCKALDH1A1ATMCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108699214-A | Isocyanate-modified rigid thermoplastic polymer composition | 伊士曼化工公司 | 2018-10-23 | — | — | CN | disclosed |
| CN-108699213-A | Isocyanate-modified hard thermoplastic polymer composition | 伊士曼化工公司 | 2018-10-23 | — | — | CN | disclosed |