Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 2/20 | 0.65 |
| ▸ | PLAU | P00749 | 7/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | LCK | P06239 | 1/20 | 0.57 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.56 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.56 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.56 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 2/20 | 0.55 |
| ▸ | CA2 | P00918 | 2/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | CA7 | P43166 | 1/20 | 0.55 |
| ▸ | XDH | P47989 | 1/20 | 0.55 |
| ▸ | CA9 | Q16790 | 1/20 | 0.55 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.55 |
| ▸ | PLAT | P00750 | 2/20 | 0.55 |
| ▸ | PLG | P00747 | 1/20 | 0.55 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7744919 | 0.93 | KDM4E (0.59) | PTPN11PLAUTSHRLCKCYP19A1 | |
| SCHEMBL29365729 | 0.92 | PTPN11 (0.68) | PTPN11PLAUTSHRLCKCYP19A1 | |
| SCHEMBL69025 | 0.92 | PTPN11 (0.68) | PTPN11PLAUTSHRLCKCYP19A1 | |
| SCHEMBL8732524 | 0.90 | PTPN11 (0.66) | PTPN11PLAUTSHRLCKCYP19A1 | |
| SCHEMBL427151 | 0.90 | TSHR (0.71) | TSHRLOXL2CA1CA2CA12 | |
| SCHEMBL34953 | 0.89 | TSHR (0.70) | TSHRLOXL2CA1CA2CA12 | |
| SCHEMBL1003761 | 0.88 | KDM4E (0.62) | PTPN11PLAUTSHRLCKCYP19A1 | |
| SCHEMBL9979782 | 0.88 | PTPN11 (0.64) | PTPN11PLAUTSHRLCKCYP19A1 | |
| SCHEMBL8054504 | 0.87 | TSHR (0.67) | TSHRLOXL2CA1CA2CA12 | |
| SCHEMBL10941453 | 0.87 | TSHR (0.67) | TSHRLOXL2CA1CA2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6232054-B1 | TEAR STRENGTH IN THE TRANSVERSE DIRECTION (TD) OF 10 TO 100 G, A BREAK STRENGTH IN TD OF 10 TO 40 KG/MM.2, A BREAK STRENGTH IN THE MACHINE DIRECTION (MD) OF 2 TO 25 KG/MM.2 AND A THICKNESS UNEVENNESS IN MD OF 0 TO 8 MU.M. | FUJI PHOTO FILM CO., LTD. (JP) | 2001-05-15 | — | — | US | disclosed |