Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC34A1 | Q06495 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.32 |
| ▸ | TYMS | P04818 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL28319551 | 0.92 | SLC34A1 (0.47) | SLC34A1TSHRKDM4EMMP2THRB | |
| Phosphoric Acid SCHEMBL29000754 | 0.89 | SLC34A1 (0.44) | SLC34A1TSHRKDM4EMMP2THRB | |
| Phosphoric Acid SCHEMBL8740021 | 0.88 | SLC34A1 (0.50) | SLC34A1TSHRLMNATYMS | |
| Phosphoric Acid SCHEMBL9680822 | 0.88 | SLC34A1 (0.50) | SLC34A1TSHRLMNATYMS | |
| Phosphoric Acid SCHEMBL16926985 | 0.85 | SLC34A1 (0.57) | SLC34A1TSHRKDM4EMMP2THRB | |
| Phosphoric Acid SCHEMBL28203319 | 0.85 | SLC34A1 (0.47) | SLC34A1TSHRKDM4EMMP2LMNA | |
| Phosphoric Acid SCHEMBL3972151 | 0.83 | SLC34A1 (0.80) | SLC34A1KDM4EMMP2THRBMAPK1 | |
| Phosphoric Acid SCHEMBL29228042 | 0.83 | SLC34A1 (0.80) | SLC34A1KDM4EMMP2THRBMAPK1 | |
| Phosphoric Acid SCHEMBL3947 | 0.83 | — | — | |
| Phosphoric Acid SCHEMBL28340109 | 0.83 | SLC34A1 (0.47) | SLC34A1MMP2PPARDCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110105452-A | Arm plate protein-4 D binding molecule is used to adjust the purposes of blood brain barrier permeability | 瓦西尼斯公司 | 2019-08-09 | — | — | CN | disclosed |
| CN-108697778-A | Pathogen vaccines and methods of making and using the same | 哈佛学院院长等 | 2018-10-23 | — | — | CN | disclosed |