Phosphoric Acid

Phosphoric Acid

SCHEMBL9680822

O=P([O-])([O-])[O-].OCCO.OCCO.OCCO.[K+].[K+].[K+]

nearest known ligand 0.50

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Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
SLC34A1 Q06495 1/20 0.50
TSHR P16473 1/20 0.42
LMNA P02545 2/20 0.35
TYMS P04818 1/20 0.33
ALDH1A1 P00352 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
CAMK2A Q9UQM7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphoric Acid SCHEMBL8740021 1.00 SLC34A1 (0.50) SLC34A1TSHRLMNATYMSALDH1A1
Phosphoric Acid SCHEMBL28203319 0.96 SLC34A1 (0.47) SLC34A1TSHRLMNATYMS
Phosphoric Acid SCHEMBL11212324 0.92 TSHR (0.42) SLC34A1TSHRLMNATYMSALDH1A1
Phosphoric Acid SCHEMBL27922068 0.92 TSHR (0.42) SLC34A1TSHRLMNATYMSALDH1A1
Phosphoric Acid SCHEMBL9419903 0.92 TSHR (0.42) SLC34A1TSHRLMNATYMSALDH1A1
Phosphoric Acid SCHEMBL359167 0.92 TSHR (0.42) SLC34A1TSHRLMNATYMSALDH1A1
Phosphoric Acid SCHEMBL31519804 0.92 TSHR (0.42) SLC34A1TSHRLMNATYMSALDH1A1
Phosphoric Acid SCHEMBL28247463 0.88 SLC34A1 (0.57) SLC34A1TSHRLMNATYMS
Phosphoric Acid SCHEMBL9695789 0.85 LMNA (0.37) SLC34A1TSHRLMNATYMS
Phosphoric Acid SCHEMBL10603468 0.85 TSHR (0.36) SLC34A1TSHRLMNATYMS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5110733-A Separation and purification of biomaterials with ion exchange resins ROHM AND HAAS COMPANY (US) 1992-05-05 US claimed
EP-0245985-B1 LIQUID-LIQUID EXTRACTION METHOD USING PARTICULATE POLYMERIC ADSORBENT ROHM AND HAAS COMPANY (US) 1991-06-26 EP claimed
EP-0245985-A2 Liquid-liquid extraction method using particulate polymeric adsorbent ROHM AND HAAS COMPANY (US) 1987-11-19 EP claimed
CN-107532195-B Method for separating extracellular vesicles by using aqueous two-phase system 浦项工科大学校产学协力团 2021-06-22 CN disclosed
US-11016009-B2 Method for isolating extracellular vesicles using aqueous two-phase system POSTECH ACADEMY-INDUSTRY FOUNDATION (KR) 2021-05-25 US disclosed
US-20200188918-A1 NOVEL METHOD FOR ISOLATING EXTRACELLULAR VESICLES KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2020-06-18 US disclosed
US-10590372-B2 Multi-stage purification method and apparatus of extracellular vesicles using aqueous solution two-phase system POSTECH ACADEMY-INDUSTRY FOUNDATION (KR) 2020-03-17 US disclosed
US-20180164197-A1 METHOD FOR ISOLATING EXTRACELLULAR VESICLES USING AQUEOUS TWO-PHASE SYSTEM THE REGENTS OF THE UNIVERSITY OF MICHIGAN 2018-06-14 US disclosed
US-20180105778-A1 MULTI-STAGE PURIFICATION METHOD AND APPARATUS OF EXTRACELLULAR VESICLES USING AQUEOUS SOLUTION TWO-PHASE SYSTEM POSTECH ACADEMY-INDUSTRY FOUNDATION (KR) 2018-04-19 US disclosed
EP-3279332-A1 METHOD FOR ISOLATING EXTRACELLULAR VESICLES USING AQUEOUS TWO-PHASE SYSTEM Postech Academy-Industry Foundation (KR) 2018-02-07 EP disclosed
CN-107532195-A The method that extracellular vesica is separated using double-aqueous phase system 浦项工科大学校产学协力团 2018-01-02 CN disclosed
CN-100575483-C The method for preparing heat resistant xylanase, heat-resisting xylobiase or heat-resisting beta-glucosidase UNIV CHINA AGRICULTURAL 2009-12-30 CN disclosed
CN-101012457-A Method of preparing heat-proof xylanase, heat-proof beta-xylosidase or heat-proof beta-glucosidase UNIV CHINA AGRICULTURAL (CN) 2007-08-08 CN disclosed
US-5162221-A FRUCTOSE-1,6-BISPHOSPHATE ALDOLASE, A PROCESS FOR THE PREPARATION THEREOF AND ITS USE FORSCHUNGSZENTRUM JUELICH GMBH (DE) 1992-11-10 US disclosed