Tert-Butyl Hydroperoxide

Tert-Butyl Hydroperoxide

SCHEMBL28247696

CC(C)(C)OO.CCCCC

nearest known ligand 0.60

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Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.60
TSHR P16473 5/20 0.47
LMNA P02545 3/20 0.47
THRB P10828 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
HSD17B10 Q99714 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
CES2 O00748 3/20 0.32
CES1 P23141 2/20 0.32
ANPEP P15144 1/20 0.32
ADRB2 P07550 1/20 0.32
ADRB1 P08588 1/20 0.32
ADRB3 P13945 1/20 0.32
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
SMPD1 P17405 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tert-Butyl Hydroperoxide SCHEMBL27266819 0.93 ALDH1A1 (0.60) ALDH1A1TSHRLMNATHRBSMN1; SMN2
Nonane SCHEMBL10465898 0.90 ALDH1A1 (0.56) ALDH1A1TSHRLMNATHRBSMN1; SMN2
Decane SCHEMBL503047 0.90 ALDH1A1 (0.56) ALDH1A1TSHRLMNATHRBSMN1; SMN2
Octane SCHEMBL5960977 0.90 ALDH1A1 (0.56) ALDH1A1TSHRLMNATHRBSMN1; SMN2
Hexadecane SCHEMBL16712179 0.90 ALDH1A1 (0.56) ALDH1A1TSHRLMNATHRBSMN1; SMN2
Tert-Butyl Hydroperoxide SCHEMBL27389585 0.86 ALDH1A1 (0.69) ALDH1A1TSHR
Tert-Butyl Hydroperoxide SCHEMBL8125721 0.85 ALDH1A1 (0.61) ALDH1A1TSHRLMNATHRBSMN1; SMN2
Tert-Butyl Hydroperoxide SCHEMBL11619371 0.83 ALDH1A1 (0.47) ALDH1A1TSHRLMNATHRBMEN1
Tert-Butyl Hydroperoxide SCHEMBL8131481 0.83 ALDH1A1 (0.47) ALDH1A1TSHRLMNATHRBMEN1
Tert-Butyl Hydroperoxide SCHEMBL788774 0.78 ALDH1A1 (1.00) ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108699400-A The solidification of anaerobism composition 汉高知识产权控股有限责任公司 2018-10-23 CN disclosed