Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | THRB | P10828 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | CES2 | O00748 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | DNM1 | Q05193 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hexadecane SCHEMBL16712179 | 1.00 | ALDH1A1 (0.56) | ALDH1A1TSHRTHRBLMNAMEN1 | |
| Octane SCHEMBL5960977 | 1.00 | ALDH1A1 (0.56) | ALDH1A1TSHRTHRBLMNAMEN1 | |
| Nonane SCHEMBL10465898 | 1.00 | ALDH1A1 (0.56) | ALDH1A1TSHRTHRBLMNAMEN1 | |
| Tert-Butyl Hydroperoxide SCHEMBL27266819 | 0.97 | ALDH1A1 (0.60) | ALDH1A1TSHRTHRBLMNAMEN1 | |
| Tert-Butyl Hydroperoxide SCHEMBL28247696 | 0.90 | ALDH1A1 (0.60) | ALDH1A1TSHRTHRBLMNAMEN1 | |
| Tert-Butyl Hydroperoxide SCHEMBL27389585 | 0.83 | ALDH1A1 (0.69) | ALDH1A1TSHR | |
| Tert-Butyl Hydroperoxide SCHEMBL8125721 | 0.82 | ALDH1A1 (0.61) | ALDH1A1TSHRTHRBLMNAMEN1 | |
| Heptanoate SCHEMBL27428584 | 0.82 | GPR84 (0.71) | ALDH1A1TSHRLMNAMEN1KMT2A | |
| Dodecanoate SCHEMBL27278835 | 0.82 | GPR84 (0.71) | ALDH1A1TSHRLMNAMEN1KMT2A | |
| Tert-Butyl Hydroperoxide SCHEMBL8131481 | 0.80 | ALDH1A1 (0.47) | ALDH1A1TSHRTHRBLMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116003239-B | Bicyclic diterpenoid derivative, preparation method and application thereof | 上海中医药大学 | 2024-05-17 | — | — | CN | claimed |
| CN-116924430-A | Micro-mesoporous composite titanium-containing borosilicate molecular sieve, and preparation method and application thereof | 华东师范大学 | 2023-10-24 | — | — | CN | claimed |
| CN-116003239-A | Bicyclic diterpenoid derivative, preparation method and application thereof | 上海中医药大学 | 2023-04-25 | — | — | CN | claimed |
| CN-113831303-A | Method for preparing hexafluoropropylene oxide by epoxidation of hexafluoropropylene | 浙江大学衢州研究院 | 2021-12-24 | — | — | CN | claimed |
| CN-105541734-B | Method for efficiently preparing quinazolinone compound | 江西师范大学 | 2018-09-18 | — | — | CN | claimed |
| US-20240207410-A1 | STABILIZED LIQUID COMPOSITIONS COMPRISING A LEVODOPA-TYROSINE CONJUGATE AND USES THEREOF | NEURODERM, LTD. (IL) | 2024-06-27 | — | — | US | disclosed |
| CN-116003239-B | Bicyclic diterpenoid derivative, preparation method and application thereof | 上海中医药大学 | 2024-05-17 | — | — | CN | disclosed |
| CN-117964581-A | Method for epoxidation reaction of pinene | 中国石油化工股份有限公司 | 2024-05-03 | — | — | CN | disclosed |
| CN-117945962-A | Synthesis method of bicalutamide | 中国人民大学 | 2024-04-30 | — | — | CN | disclosed |
| CN-117736164-A | Preparation method of hexafluoropropylene oxide | 内蒙古永和氟化工有限公司 | 2024-03-22 | — | — | CN | disclosed |
| EP-4305049-A1 | STABILIZED LIQUID COMPOSITIONS COMPRISING A LEVODOPA-TYROSINE CONJUGATE AND USES THEREOF | Neuroderm Ltd (IL) | 2024-01-17 | — | — | EP | disclosed |
| CN-115337929-B | Composite carbon material loaded with aluminum monoatoms and iron monoatoms and preparation method and application thereof | 宁波杭州湾新材料研究院 | 2023-11-10 | — | — | CN | disclosed |
| US-7816401-B2 | Process for total synthesis of pladienolide B and pladienolide D | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2010-10-19 | — | — | US | disclosed |
| US-20100204490-A1 | PROCESS FOR TOTAL SYNTHESIS OF PLADIENOLIDE B AND PLADIENOLIDE D | KANADA REGINA MIKIE | 2010-08-12 | — | — | US | disclosed |
| EP-2145886-A1 | TWELVE-MEMBERED CYCLOMACROLACTAM DERIVATIVE | Eisai R&D Management Co., Ltd. (JP) | 2010-01-20 | — | — | EP | disclosed |
| US-20090286968-A1 | 2-Quinoxalinol Salen Compounds and Uses Thereof | AUBURN UNIVERSITY (US) | 2009-11-19 | — | — | US | disclosed |
| US-20080312317-A1 | 12 MEMBERED-RING MACROLACTAM DERIVATIVES | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2008-12-18 | — | — | US | disclosed |
| CN-101282967-A | Total synthesis of pladienolide b and pladienolide D | EISAI R&D MAN CO LTD (JP) | 2008-10-08 | — | — | CN | disclosed |
| EP-1935893-A1 | TOTAL SYNTHESIS OF PLADIENOLIDE B AND PLADIENOLIDE D | Eisai R&D Management Co., Ltd. (JP) | 2008-06-25 | — | — | EP | disclosed |
| US-20080021226-A1 | Process for total synthesis of pladienolide B and pladienolide D | EISAI R&D MANAGEMENT CO., LTD. | 2008-01-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080312317-A1 | 12 MEMBERED-RING MACROLACTAM DERIVATIVES | HDAC11, HDAC1, HDAC3 | ALDH1A1 2190/4885TSHR 693/4885THRB 1853/4885 |
| US-20240207410-A1 | STABILIZED LIQUID COMPOSITIONS COMPRISING A LEVODOPA-TYROSINE CONJUGATE AND USES THEREOF | COMT, TH, DDT | ALDH1A1 398/4885TSHR 2036/4885THRB 2537/4885 |
| US-20090286968-A1 | 2-Quinoxalinol Salen Compounds and Uses Thereof | NQO1, NQO2, SQOR | ALDH1A1 1265/4885TSHR 4448/4885THRB 4495/4885 |
| US-20100204490-A1 | PROCESS FOR TOTAL SYNTHESIS OF PLADIENOLIDE B AND PLADIENOLIDE D | CYP8B1, PLA2G2D, HPD | ALDH1A1 2637/4885TSHR 2691/4885THRB 1685/4885 |
| US-20080021226-A1 | Process for total synthesis of pladienolide B and pladienolide D | TPD52L2, CYP8B1, HPD | ALDH1A1 2011/4885TSHR 2611/4885THRB 2535/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.