SCHEMBL2824770

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2827695	0.85	FFAR1 (0.52)	FFAR1FFAR4PTGDR2PPARGPPARD
	SCHEMBL2827698	0.85	FFAR1 (0.52)	FFAR1FFAR4PTGDR2PPARGPPARD
	SCHEMBL3629750	0.84	FFAR1 (0.60)	FFAR1FFAR4PTGDR2
	SCHEMBL2825472	0.83	TP53 (0.49)	FFAR1FFAR4GABRA1GABRB2TP53
	SCHEMBL3631131	0.81	HDAC1 (0.48)	TP53
	SCHEMBL2828470	0.80	FFAR1 (0.62)	FFAR1FFAR4AKR1B1TP53MDM2
	SCHEMBL3632256	0.80	FFAR1 (0.48)	FFAR1FFAR4PTGDR2TP53MDM2
	SCHEMBL2830042	0.79	FFAR1 (0.61)	FFAR1FFAR4PTGDR2AKR1B1
	SCHEMBL3628789	0.78	HDAC1 (0.48)	PTGDR2TP53
	SCHEMBL3630656	0.78	FFAR1 (0.48)	FFAR1FFAR4PTGDR2TP53MDM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.