Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F7 | P08709 | 1/20 | 0.81 |
| ▸ | F3 | P13726 | 1/20 | 0.81 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.81 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.81 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.81 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.81 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.81 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.81 |
| ▸ | SIRT4 | Q9Y6E7 | 1/20 | 0.81 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | APP | P05067 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.55 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.55 |
| ▸ | MKNK1 | Q9BUB5 | 3/20 | 0.54 |
| ▸ | MKNK2 | Q9HBH9 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Niacinamide SCHEMBL27671762 | 0.90 | F7 (0.92) | F7F3SARM1SIRT2SIRT6 | |
| Niacinamide SCHEMBL5712652 | 0.90 | F7 (0.92) | F7F3SARM1SIRT2SIRT6 | |
| Niacinamide SCHEMBL2926 | 0.90 | — | — | |
| Niacinamide SCHEMBL19978192 | 0.90 | — | — | |
| Niacinamide SCHEMBL29624874 | 0.90 | — | — | |
| Niacinamide SCHEMBL460466 | 0.90 | F7 (1.00) | F7F3SARM1SIRT2SIRT6 | |
| Niacinamide SCHEMBL28209434 | 0.89 | F7 (0.76) | F7F3SARM1SIRT2SIRT6 | |
| Niacinamide SCHEMBL28744959 | 0.89 | F7 (0.88) | F7F3SARM1SIRT2SIRT6 | |
| Niacinamide SCHEMBL4101623 | 0.89 | F7 (0.88) | F7F3SARM1SIRT2SIRT6 | |
| Niacinamide SCHEMBL20298468 | 0.89 | F7 (0.88) | F7F3SARM1SIRT2SIRT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108558830-B | A kind of synthetic method of nicosulfuron raw medicine | 河南恒诚药业有限公司 | 2019-09-20 | — | — | CN | claimed |
| CN-108558830-A | A kind of synthetic method of nicosulfuron active compound | 河南恒诚药业有限公司 | 2018-09-21 | — | — | CN | claimed |