SCHEMBL2824830

SCHEMBL2824830

COCCN(C)CCn1cc(C(=O)O)cn1

nearest known ligand 0.56

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.56
EGLN1 Q9GZT9 3/20 0.40
CYP4F2 P78329 1/20 0.39
CYP4A11 Q02928 1/20 0.39
KDM5C P41229 1/20 0.36
PLA2G4A P47712 1/20 0.35
IGF1R P08069 1/20 0.35
HCAR3 P49019 2/20 0.35
ALKBH1 Q13686 2/20 0.34
HPGDS O60760 1/20 0.34
ALKBH2 Q6NS38 1/20 0.34
ALDH1A1 P00352 1/20 0.34
LMNA P02545 1/20 0.34
MAPT P10636 1/20 0.34
CYP2C19 P33261 1/20 0.34
GFER P55789 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
KAT2B Q92831 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2828291 0.84 L3MBTL1 (0.68) L3MBTL1EGLN1CYP4F2CYP4A11PLA2G4A
SCHEMBL2826039 0.81 L3MBTL1 (0.68) L3MBTL1CYP4F2CYP4A11PLA2G4AALKBH1
SCHEMBL370482 0.75 L3MBTL1 (0.62) L3MBTL1EGLN1CYP4F2CYP4A11PLA2G4A
SCHEMBL4240582 0.73 L3MBTL1 (1.00) L3MBTL1EGLN1CYP4F2CYP4A11PLA2G4A
SCHEMBL18397011 0.72 L3MBTL1 (0.50) L3MBTL1ALDH1A1
SCHEMBL27175170 0.71 L3MBTL1 (0.46) L3MBTL1ALDH1A1LMNAMAPTCYP2C19
SCHEMBL23535650 0.71 L3MBTL1 (0.50) L3MBTL1IGF1RHCAR3ALDH1A1
SCHEMBL30590951 0.71 L3MBTL1 (0.53) L3MBTL1CYP4F2CYP4A11PLA2G4AALDH1A1
SCHEMBL18038382 0.71 L3MBTL1 (0.71) L3MBTL1EGLN1CYP4F2CYP4A11PLA2G4A
SCHEMBL22183009 0.71 L3MBTL1 (0.49) L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120189489-A Composition for treating neurodegenerative diseases, preparation method and application thereof 深圳康普生物药业有限公司 2025-06-24 CN disclosed
EP-1773827-B1 BENZOTHIAZOLE DERIVATIVES HOFFMANN LA ROCHE (CH) 2010-02-17 EP disclosed
US-7371749-B2 Benzothiazole derivatives HOFFMANN-LA ROCHE INC. (US) 2008-05-13 US disclosed
EP-1773827-A1 BENZOTHIAZOLE DERIVATIVES F.HOFFMANN-LA ROCHE AG (CH) 2007-04-18 EP disclosed
US-20060019949-A1 Benzothiazole derivatives HOFFMANN-LA ROCHE INC. 2006-01-26 US disclosed
WO-2006008041-A1 BENZOTHIAZOLE DERIVATIVES F. HOFFMANN-LA ROCHE AG (CH) 2006-01-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060019949-A1 Benzothiazole derivatives CNR2, CNR1, CHRNA2 L3MBTL1 1615/4885EGLN1 1007/4885CYP4F2 566/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.